Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 49764-63-8, name is 4,5-Dibromobenzene-1,2-diamine, A new synthetic method of this compound is introduced below., Recommanded Product: 4,5-Dibromobenzene-1,2-diamine
This compound was synthesized according to a modified literature procedure. 30 Cylcohexane octahydrate SM4 (1.17 g, 3.76 mmol), 4,5-dibromo benzene-1,2-diamine QZ-IB-8 (3.00 g, 11.3 mmol) were refluxed in 450 ml of glacial acetic acid (additional volume of glacial acetic acid was added because the solution was hard to stir), for 24 hours at 140 C. The solution was then filtered and the obtained powder was washed with 120 ml of hot glacial acetic acid and was then refluxed in 200 ml of 30 % nitric acid for 23 hours. The solution was filtered to yield 3.06 g (95 %) of greenish powder. (at)H (300 MHz, DMSO-d6) 88.97 (s, 6H). MALDI-TOF MS (MH+H) : m/z 853.5, 855.5, 857.5,859.5, 861.5, 863.5; calcd for C24H7Br6N6, 858.8. An amount of 1 g was sublimed under high vacuum (ca. 10-6 torr) at ca. 400 C. An amount of 252 mg of yellow solid was isolated. Anal. Calcd. for C24H6Br6N6: C, 33.61, H, 0.71, Br, 55.89, N, 9.80. Found: C, 33.74, H, 0.75, Br, 55.66, N, 9.55.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; GEORGIA TECH RESEARCH CORPORATION; WO2005/123737; (2005); A2;,
Bromide – Wikipedia,
bromide – Wiktionary