Electric Literature of 608-30-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 608-30-0, name is 2,6-Dibromoaniline belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
A 200 mL flask replaced with nitrogen was charged with 10 g of 2,6-dibromoaniline, 120 g of chloroform and 4.8 g of triethylamine. To the resulting mixture was added dropwise 6 g of oxalyl chloride at 0 C. over 30 minutes. The resulting mixture was stirred at 0 C. for 2 hours and, thereafter, was stirred at room temperature for 18 hours. By adding 100 g of water to the resulting reaction mixture, a crystal was precipitated. Then, after the precipitated crystal was recovered by filtering operation, the obtained substance was washed with 10 g of water and 20 g of diethyl ether, and further dried to obtain 9.2 g of a white crystal. It was confirmed by gas chromatography/mass spectrometry (GC-MS) that the resulting white crystal is N,N?-bis(2,6-dibromophenyl)ethanediamide. Yield: 84%. [0070] MS (m/z): 555 (M+)
The synthetic route of 2,6-Dibromoaniline has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; Hagiya, Koji; US2013/281709; (2013); A1;,
Bromide – Wikipedia,
bromide – Wiktionary