Related Products of 69272-50-0,Some common heterocyclic compound, 69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine, molecular formula is C6H6Br2N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1) Preparation of 5,8-dibromo-2,3-bis(phenyl)quinoxaline, the Chemical Equation Thereof is The detailed preparation procedure is as follows: 3,6-dibromo-o-phenylene diamine (1.0 g, 3.7 mmol) was added to a solution of compound benzil (0.39 g, 1.84 mmol) in acetic acid (20 mL) at 120?, then the mixture was mixed uniformly. After refluxed for 12 hours, the fluid reactant was poured into water, and neutralized with sodium bicarbonate until neutral, then extracted with chloroform and washed with saturated brine, dried over anhydrous sodium sulfate, then it was vacuum evaporated to remove the solvent, and the resulting crude product was purified by column chromatography to give a white solid, and then it was purified by recrystallization from chloroform/n-hexane to give a white solid powder. The test result is: MS (EI) m/z: 440(M+).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3,6-Dibromobenzene-1,2-diamine, its application will become more common.
Reference:
Patent; Ocean’s King Lighting Science & Technology Co., Ltd.; Zhou, Mingjie; Huang, Jie; Xu, Erjian; US8853348; (2014); B2;,
Bromide – Wikipedia,
bromide – Wiktionary