Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 68322-84-9, name is 2-Bromo-1-fluoro-4-(trifluoromethyl)benzene, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 2-Bromo-1-fluoro-4-(trifluoromethyl)benzene
Example 2 [0028] [0029] A 400 mL shaker tube was loaded with 50 g of 3-bromo-4-fluorobenzotrifluoride and 10 g of SbF5. The shaker tube was evacuated, charged with 20 g of TFE, and agitated for 12 h at 25 C. The crude product was unloaded from the shaker tube and washed with water. The organic layer was separated, dried over MgSO4 and filtered to give 37 g of crude product, containing benzotrifluoride and compounds 4 and 5 in a ratio of 10:60:30, respectively, as determined by NMR and GC/MS. The reaction mixture was distilled at atmospheric pressure, using a spinning-band distillation column to give 15.3 g of a fraction (b.p. 142-144 C. at 760 mm Hg) and 13.5 g of residue. According to NMR analysis, the distilled fraction contained compounds 4 and 5 in a ratio of 85:15. The residue was found to be a mixture of 4 and 5 in a ratio of 30:70. [0030] Compound 4. 19F NMR (CDCI3): -80.38 (3F,t), -101.28 (1F, m), -111.56 (2F,m), -126.61(2F, s) ppm. H1 NMR (CDCl3): 7.32 (1H,m), 7.70 (1H,m), 7.92 (1H,m) ppm. [0031] Compound 5. 19F NMR (CDCl3): -79.33 (6F, m)), -102.46 (1F,m), -120.33 (4F, A:B quartet), -181.75, 1F, m) ppm. H1 NMR (CDCl3): 7.32 (1H,m), 7.70 (1H,m), 7.92 (1H,m) ppm.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 68322-84-9.
Reference:
Patent; E I DU PONT DE NEMOURS AND COMPANY; Petrov, Viacheslav A.; US2014/200372; (2014); A1;,
Bromide – Wikipedia,
bromide – Wiktionary