In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 261723-28-8, name is (3-Bromo-2-fluorophenyl)methanamine belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Product Details of 261723-28-8
TEA (2.11 g, 20.88 mmol) and B0C2O (1.67 g, 7.66 mmol) were added to a solution of Compound BDl l-4 (1.42 g, 6.96 mmol) in DCM (30.00 mL). The mixture was stirred at 15C for 12 hours. LCMS showed the production of BD11-5. The reaction was concentrated to give a residue. The residue was purified by column chromatography (S1O2, petroleum ether: ethyl acetate mixture with a ratio of 30: 1 to 10: 1) to afford Compound BD11-5 (2.00 g, crude) as a white solid.
The synthetic route of 261723-28-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; THE BROAD INSTITUTE, INC.; VACCA, Joseph, P.; (103 pag.)WO2018/75871; (2018); A1;,
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