Adding a certain compound to certain chemical reactions, such as: 1647-26-3, name is 1-Bromo-2-cyclohexylethane, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1647-26-3, HPLC of Formula: C8H15Br
The title compound was prepared by General Method 2. p-tolylhydrazine hydrochloride (0.96g, 6.0mmol) was added to a vigorously stirred mixture of tetra-n-butylammonium chloride (84mg, 0.3mmol) in 50% aqueous sodium hydroxide (6mL) followed by 2-cyclohexylethyl bromide (1.26g, 6.6mmol). The mixture was heated at 60 0C (oil bath temp.) for 6h. After cooling to room temperature, water (20-3OmL) was added and the mixture extracted with chloroform (3 x 1OmL). The total extract was dried (sodium sulfate), evaporated in vacuo to give a dark oil (1.49g) which was chromatographed (45g of silica gel, eluted with dichloromethane) to give the product as a yellow-orange oil (0.68g, 2.93mmol, 48.8%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromo-2-cyclohexylethane, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; MEDIVATION TECHNOLOGIES, INC.; WO2009/120717; (2009); A2;,
Bromide – Wikipedia,
bromide – Wiktionary