Some common heterocyclic compound, 4333-56-6, name is Bromocyclopropane, molecular formula is C3H5Br, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 4333-56-6
guanidine hydrochloride 100 kg with the bromo cyclopropane 126.6 kg placed in 800 kg in acetone, then adding the potassium carbonate 174.6 kg, heating to 50 C, reaction 3.5h, dropped to room temperature after-filtration, the filtrate is concentrated under reduced pressure to dry, to produce an intermediate 198.6 kg, molar yield 95%;
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4333-56-6, its application will become more common.
Reference:
Patent; QILU SYNVA PHARMACEUTICAL CO., LTD.; LIU, ZHI; KONG, QINGWEN; FANG, MINGFENG; LIU, QUANCAI; KONG, MEI; WU, LIANYONG; (6 pag.)CN104649982; (2016); B;,
Bromide – Wikipedia,
bromide – Wiktionary