In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 608-30-0 as follows. name: 2,6-Dibromoaniline
Example 51 trans-N- (6-Bromo-2, 3,4, 14b-tetrahydro-1 H-dibenzo [b, qpyrido [1, 2-d] [1,4] oxazepin- 1-yl)-2, 2, 2-trifluoroacetamide (Structure 36 of scheme IX where X = O, R1 = H, R2 = H, R3 = H, R4 = Br, R5 = H, R10 = H) 2-[(2,6-Dibromophenyl)iminomethyl]phenol (Structure 30 of scheme VIII where R2 = H) General method 19: Formation of an imine of Structure 30 out of an amine and an aldehyde. A solution of 2, 6-dibromoaniline (9 g, 35.9 mmol), salicylaldehyde (2.79 mL, 35.9 mmol) and p-toluenesulfonic acid (20 mg, 0.1 mmol) in toluene (180 mL) was heated to reflux in a Dean-Stark apparatus for 2 h. After adding some triethylamine the reaction mixture was evaporated resulting in crude compound 2- 6- dibromophenyl) iminomethyllphenol (14 g, 100%).
According to the analysis of related databases, 608-30-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; AKZO NOBEL N.V.; WO2003/84963; (2003); A1;,
Bromide – Wikipedia,
bromide – Wiktionary