Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 108-85-0, name is Bromocyclohexane, A new synthetic method of this compound is introduced below., Formula: C6H11Br
General procedure: A mixture of organic halide or epoxide (1.0 mmol), sodium azide(1.2 mmol), and alkyne (1.0 mmol) was stirred in water (3.0 mL) assolvent. Then, Cu(Bb)(PCy3) (5 mg) was added to the reaction mixtureand it was further stirred at 60 C for a period of time. After completionof the reaction (monitored by TLC), the reaction mixture was extractedby ethyl acetate (5 mL, 3 times) and dried over anhydrous Na2SO4 andthe procedure was followed by concentration under reduced pressure.The crude products were purified by column chromatography on silicagel (silica gel, n-hexane-EtOAc) to give the pure products.
The synthetic route of 108-85-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Khalili, Dariush; Evazi, Roya; Neshat, Abdollah; Aboonajmi, Jasem; Osanlou, Farzane; Inorganica Chimica Acta; vol. 506; (2020);,
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