Adding a certain compound to certain chemical reactions, such as: 1647-26-3, name is 1-Bromo-2-cyclohexylethane, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1647-26-3, Safety of 1-Bromo-2-cyclohexylethane
The commercially available compound 25-b (0.95 g, 5.0 mmol), triphenylphosphine (2.62 g, 10.0 mmol) and toluene(25 mL) was heated at reflux for 16 hours and then cooled to room temperature. The reaction mixture was filtered and the resulting solid was extracted with acetic acidEthyl ester, and vacuum dried to give compound 25-a (1.50 g, 66%) as a white solid.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-Bromo-2-cyclohexylethane, and friends who are interested can also refer to it.
Reference:
Patent; Shanghai Yingli Pharmaceutical Co., Ltd.; Xu Zusheng; Lou Yangtong; Wu Tianzhi; (87 pag.)CN106478634; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary