Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 837-52-5, is researched, SMILESS is C1=C(Cl)C=C2C(=C1)C(=CC=N2)N3CCNCC3, Molecular C13H14ClN3Journal, Medicinal Chemistry Research called Synthesis and biological activity of novel amidrazones incorporating 5-nitroimidazole, ciprofloxacin, and 7-chloro-4-piperazinylquinoline, Author is Saadeh, Haythem A.; Al-Qaoud, Khaled M.; Abu-Qatouseh, Luay F.; Shihab, Penelope A.; Kaur, Hargobinder; Goyal, Kapil; Sehgal, Rakesh; Mubarak, Mohammad S., the main research direction is amidrazone nitroimidazole ciprofloxacin chloropiperazinylquinoline preparation antitumor antibacterial parasiticide.Electric Literature of C13H14ClN3.
Series of new amidrazones incorporating 5-nitroimidazole (a), ciprofloxacin (b), and 7-chloro-4-piperazinylquinoline (c) moieties, were synthesized by reacting hydrazonoyl chlorides , derived from 4-fluoroaniline and 4-chloroaniline with the proper amine, in the presence of triethylamine. Structures of the prepared compounds were confirmed by 1H NMR, 13C NMR, and ESI-HRMS spectral data. The antitumor, antibacterial, and antiparasitic activities of the newly synthesized compounds were evaluated.
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Reference:
Bromide – Wikipedia,
bromide – Wiktionary