The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 7-Chloro-4-(piperazin-1-yl)quinoline, is researched, Molecular C13H14ClN3, CAS is 837-52-5, about Studies on aminoquinolines. Chemical, antiparasitic, antimicrobial and antifungal studies of 4-(4-mono-, di- and trichloroacetyl-1-piperazinyl)quinolines, the main research direction is chloroacetylpiperazinylquinoline preparation pharmacol; piperazinylquinoline preparation pharmacol; quinoline piperazinyl preparation pharmacol; parasiticide chloroacetylpiperazinylquinoline; fungicide chdloroacetylpiperazinylquinoline; bactericide chloroacetylpiperazinylquinoline; amebicide chloroacetylpiperazinylquinoline.COA of Formula: C13H14ClN3.
Piperazinylquinolines (I, R = H, Me; R1 = H, Cl, CF3, NO2; R2 = Cl, CF3, OMe; R3 = H, CH2ClCHCl2, CCl3 and II, R = H, Me; R1 = H, NO2; R2 = H, Cl, CF3, OMe) were prepared and their pharmacol. was studied. I were prepared either by the reaction of 1-nitrosopiperazines with chloroquinolines, hydrogenolysis of the chloro(nitrosopiperazinyl)quinolines, and chloroacetylation of the resultant II or by reaction of piperazine [104667-94-9] with chloroquinolines followed by chloroacetylation. The parasiticidal, antibacterial and antifungal activities of I and II were studied in vitro. The amebicidal activity of the compounds was studied both in vitro and in vivo. The chloroacetyl derivatives showed weak bactericidal activity. The structure-activity relations of the compounds are discussed.
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Reference:
Bromide – Wikipedia,
bromide – Wiktionary