Month: September 2022

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Product Details of C5H9BrO2.

Campiani, Giuseppe;Cavella, Caterina;Osko, Jeremy D.;Brindisi, Margherita;Relitti, Nicola;Brogi, Simone;Saraswati, A. Prasanth;Federico, Stefano;Chemi, Giulia;Maramai, Samuele;Carullo, Gabriele;Jaeger, Benedikt;Carleo, Alfonso;Benedetti, Rosaria;Sarno, Federica;Lamponi, Stefania;Rottoli, Paola;Bargagli, Elena;Bertucci, Carlo;Tedesco, Daniele;Herp, Daniel;Senger, Johanna;Ruberti, Giovina;Saccoccia, Fulvio;Saponara, Simona;Gorelli, Beatrice;Valoti, Massimo;Kennedy, Breandan;Sundaramurthi, Husvinee;Butini, Stefania;Jung, Manfred;Roach, Katy M.;Altucci, Lucia;Bradding, Peter;Christianson, David W.;Gemma, Sandra;Prasse, Antje research published 《 Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors》, the research content is summarized as follows. Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by a progressive-fibrosing phenotype. IPF has been associated with aberrant HDAC activities confirmed by our immunohistochem. studies on HDAC6 overexpression in IPF lung tissues. We herein developed a series of novel hHDAC6 inhibitors, having low inhibitory potency over hHDAC1 and hHDAC8, as potential pharmacol. tools for IPF treatment. Their inhibitory potency was combined with low in vitro and in vivo toxicity. Structural anal. of 6h (I) and structure-activity relationship studies contributed to the optimization of the binding mode of the new mols. The best-performing analogs were tested for their efficacy in inhibiting fibrotic sphere formation and cell viability, proving their capability in reverting the IPF phenotype. The efficacy of analog 6h was also determined in a validated human lung model of TGF-β1-dependent fibrogenesis. The results highlighted in this manuscript may pave the way for the identification of first-in-class mols. for the treatment of IPF.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Product Details of C5H9BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 5392-10-9.

Camilo, Nilton S.;Santos, Hugo;Zeoly, Lucas A.;Fernandes, Fabio S.;Rodrigues, Manoel T. Jr.;Silva, Thiago S.;Lima, Samia R.;Serafim, Jose Claudio;de Oliveira, Aline S. B.;Carpanez, Arthur G.;Amarante, Giovanni W.;Coelho, Fernando research published 《 An Improved Protocol for the Morita-Baylis-Hillman Reaction Allows Unprecedented Broad Synthetic Scope》, the research content is summarized as follows. The effects of several Broensted acids on the rate of DABCO-catalyzed MBH reactions were evaluated. The protocol was operationally simple, involving neat and open-flask conditions and was compatible with a wide range of reagents. A general acid catalysis mechanism was suggested to be responsible for the rate increase. The synthetic versatility of the MBH adducts was exemplified with a two-steps diastereoselective synthesis of the natural product (±)-sitophilure. This acid-mediated protocol can be potentially used as a general methodol. for the MBH reaction.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Application In Synthesis of 5392-10-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Computed Properties of 629-04-9.

Camberlein, Virgyl;Kraupner, Nicolas;Bou Karroum, Nour;Lipka, Emmanuelle;Deprez-Poulain, Rebecca;Deprez, Benoit;Bosc, Damien research published 《 Multi-component reaction for the preparation of 1,5-disubstituted 1,2,3-triazoles by in-situ generation of azides and nickel-catalyzed azide-alkyne cycloaddition》, the research content is summarized as follows. An efficient one-pot procedure combining bromide conversion into azide followed by NiAAC for the preparation of 1,5-disubstituted 1,2,3-triazoles was developed. This procedure prevents the use of isolated azides, which are insufficiently com. available and could be potentially unstable and difficult to handle. Moreover this one-pot method tolerated broad range of functional moieties including ester, carbamate or alc. Diverse 1,5-disubstituted 1,2,3-triazoles were obtained from functionalized aryl and alkyl alkynes and bromides with modest to excellent yields and regioselectivities. This procedure will enable the synthesis of libraries of functionalizable 1,5-disubstituted 1,2,3-triazoles particularly helpful for diverse applications such as medicinal chem. and chem. biol. purposes.

Computed Properties of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C2H7Br2N.

Calvo-Martin, Gorka;Plano, Daniel;Sanmartin, Carmen research published 《 New Experimental Conditions for Diels-Alder and Friedel-Crafts Alquilation Reactions with Thiophene: A New Selenocyanate with Potent Activity against Cancer》, the research content is summarized as follows. The reactivity of thiophene in Diels-Alder reactions is investigated with different maleimide derivatives In this paper, we have synthesized for the first time the Diels-Alder adducts of thiophene at room temperature and atm. pressure. Maleimido-thiophene adducts were promoted by AlCl₃. The effects of solvent, time, temperature and the use of different Lewis acids were studied, showing dramatic effects for solvent and Lewis acid. Furthermore, the catalysis with AlCl₃ is highly stereoselective, preferably providing the exo form of the adduct. Addnl., we also discovered the ability of AlCl₃ to catalyze the arylation of maleimides to yield 3-aryl succinimides in a straightforward manner following a Friedel-Crafts-type addition The inclusion of a selenocyanate group contributes to the cytotoxic activity of the adduct. This derivatization (from compound 7 to compound 15) results in an average GI₅₀ value of 1.98 μM in the DTP (NCI-60) cell panel, resulting in being especially active in renal cancer cells.

COA of Formula: C2H7Br2N, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Name: Methyl 2-bromopropanoate.

Caldora, Henry P.;Govaerts, Sebastian;Dighe, Shashikant U.;Turner, Oliver J.;Leonori, Daniele research published 《 A de novo Synthesis of Oxindoles from Cyclohexanone-Derived γ-Keto-Ester Acceptors Using a Desaturative Amination-Cyclization Approach》, the research content is summarized as follows. A desaturative approach for oxindole synthesis was reported. This method used a simple Et 2-(2-oxocyclohexyl)acetates and primary amine building blocks as coupling partners. A dual photoredox-cobalt manifold was used to generate a secondary aniline that, upon heating, cyclized with the pendent ester functionality. The process operated under mild conditions and was applied to the modification of several amino acids, the blockbuster drug mexiletine, as well as the formation of dihydroquinolinones.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Name: Methyl 2-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane, Recommanded Product: 1-Bromoheptane

Cain, Caitlin N.;Trinklein, Timothy J.;Ochoa, Grant S.;Synovec, Robert E. research published 《 Tile-Based Pairwise Analysis of GC x GC-TOFMS Data to Facilitate Analyte Discovery and Mass Spectrum Purification》, the research content is summarized as follows. A new tile-based pairwise anal. workflow, termed 1v1 anal., is presented to discover and identify analytes that differentiate two chromatograms collected using comprehensive two-dimensional (2D) gas chromatog. coupled with time-of-flight mass spectrometry (GC x GC-TOFMS). Tile-based 1v1 anal. easily discovered all 18 non-native analytes spiked in diesel fuel within the top 30 hits, outperforming standard pairwise chromatog. analyses. However, eight spiked analytes could not be identified with multivariate curve resolution-alternating least-squares (MCR-ALS) nor parallel factor anal. (PARAFAC) due to background contamination. Analyte identification was achieved with class comparison enabled-mass spectrum purification (CCE-MSP), which obtains a pure analyte spectrum by normalizing the spectra to an interferent mass channel (m/z) identified from 1v1 anal. and subtracting the two spectra. This report also details the development of CCE-MSP assisted MCR-ALS, which removes the identified interferent m/z from the data prior to decomposition In total, 17 out of 18 spiked analytes had a match value (MV) > 800 with both versions of CCE-MSP. For example, MCR-ALS and PARAFAC were unable to decompose the pure spectrum of Me decanoate (MVs < 200) due to its low 2D chromatog. resolution (~0.34) and high interferent-to-analyte signal ratio (~30:1). By leveraging information gained from 1v1 anal., CCE-MSP and CCE-MSP assisted MCR-ALS obtained a pure spectrum with an average MV of 908 and 964, resp. Furthermore, tile-based 1v1 anal. was applied to track moisture damage in cacao beans, where 86 analytes with at least a 2-fold concentration change were discovered between the unmolded and molded samples. This 1v1 anal. workflow is beneficial for studies where multiple replicates are either unavailable or undesirable to save anal. time.

Recommanded Product: 1-Bromoheptane, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 19111-87-6, formula is C18H11Br, Name is 2-Bromotriphenylene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. SDS of cas: 19111-87-6.

Cai, Minghan;Song, Xiaozeng;Zhang, Dongdong;Qiao, Juan;Duan, Lian research published 《 π-π stacking: a strategy to improve the electron mobilities of bipolar hosts for TADF and phosphorescent devices with low efficiency roll-off》, the research content is summarized as follows. A series of D-π-A type bipolar hosts based on triphenylene/carbazole were designed and synthesized. π-π Stacking of the triphenylene units between two adjacent mols. renders these hosts high electron mobilities above 1 × 10^-4 cm² V^-1 s^-1, and their electron and hole mobilities can be regulated through varying the connection position and π moieties. Due to more balanced charge mobilities, a D1-based green thermally activated delayed fluorescence (TADF) device achieved the highest external quantum efficiency (EQE) of 16.3%, and its EQE could still maintain 15.3% and 13.8% at the high luminance of 5000 cd m^-2 and 10 000 cd m^-2, resp. D1-based green phosphorescent devices also exhibited the highest EQE of 18.6% with a reduced roll-off to 17.6% at 5000 cd m^-2 and 16.2% at 10 000 cd m^-2.

19111-87-6, 2-Bromotriphenylene is a useful research compound. Its molecular formula is C18H11Br and its molecular weight is 307.2 g/mol. The purity is usually 95%.
2-Bromotriphenylene is a brominating agent that has the ability to react with sodium carbonate and emit light. The luminescence of 2-bromotriphenylene can be used as an indicator of the degree of dilution, or how much water is present in a solution. It also emits light when it reacts with chloride ions in a reaction solution. 2-Bromotriphenylene can be used as a polymer matrix to form polymeric films, which are then used as catalysts for organic reactions. The luminescence properties of 2-bromotriphenylene make it suitable for use in functional theory experiments. This chemical compound is relatively low cost, and has been shown to have high yield in catalysis., SDS of cas: 19111-87-6

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Organic compounds having carbon bonded to bromine are called organic bromides. Application of C7H15Br.

Cai, Dongren;Zhan, Guowu;Xiao, Jingran;Zhou, Shu-Feng;Qiu, Ting research published 《 Design and synthesis of novel amphipathic ionic liquids for biodiesel production from soapberry oil》, the research content is summarized as follows. Biodiesel produced from non-edible oils has received intensive attention in recent years. Herein, a series of novel amphipathic ionic liquids (ILs) based on the 4-dimethylaminopyridine (DMAP) were prepared for the transesterification of soapberry oil and methanol. The structures of the prepared ILs were systematically characterized by both Fourier transform IR spectroscopy (FT-IR) and NMR (NMR, ¹H NMR and ¹³C NMR). In addition, the effects of side-chain length of cation and the number of active site (H⁺) of ILs on the biodiesel yield were investigated, and the results suggested that 1-dodecyl-(4-dimethylammonium)-pyridinium bisulfate ([C12-DMAPH][HSO₄]₂) exhibited the highest catalytic efficiency. Meanwhile, [C12-DMAPH][HSO₄]₂ was proven to be amphipathic, and the corresponding catalytic mechanism was proposed. Under the catalysis of [C12-DMAPH][HSO₄]₂, the optimum operating conditions of transesterification of soapberry oil and methanol were explored via the combination of single factor experiment and response surface methodol., obtaining the high biodiesel yield of (98.02 ± 0.36)% under the optimum operating conditions. Importantly, [C12-DMAPH][HSO₄]₂ exhibited high stability in the transesterification of soapberry oil and methanol in five consecutive runs. Furthermore, the catalytic activities of [C12-DMAPH][HSO₄]₂ towards other transesterification of non-edible oils and lower alcs. were also investigated, which indicated a general applicability of the prepared IL.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Application of C7H15Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Application of C8H6BrF3.

Cadena, Melissa;Villatoro, Roberto Silva;Gupta, Jyoti Shah;Phillips, Cody;Allen, Jonathan B.;Arman, Hadi D.;Wherritt, Daniel J.;Clanton, Nicholas A.;Ruchelman, Alexander L.;Simmons, Eric M.;DelMonte, Albert J.;Coombs, John R.;Frantz, Doug E. research published 《 Pd-Catalyzed Chemoselective O-Benzylation of Ambident 2-Quinolinone Nucleophiles》, the research content is summarized as follows. A highly chemoselective O-benzylation of ambident 2-quinolinone nucleophiles via Pd-catalysis was discovered and demonstrated. Detailed reaction anal. using direct-injection high resolution mass spectrometry (DI-HRMS) combined with in situ ³¹P NMR implicate a phosphine mono-oxide Pd(II) η¹-benzyl complex as a key intermediate on the catalytic cycle. Extrapolation of this method to selectively O-alkylate a series of substituted 2-quinolinones using several benzylic electrophiles was demonstrated providing 2-benzyloxy quinolines in good yields and high O:N selectivities (up to 100:1) utilizing as little as 1 mol % Pd-catalyst to achieve these results.

402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., Application of C8H6BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 2576-47-8, formula is C2H7Br2N, The most pervasive is the naturally produced bromomethane. HPLC of Formula: 2576-47-8

Burgess, David;Li, Na;Rosik, Nicole;Fryer, Peter J.;McRobbie, Ian;Zhang, Haining;Zhang, Zhenyu J. research published 《 Surface-Grafted Poly(ionic liquid) that Lubricates in Both Non-polar and Polar Solvents》, the research content is summarized as follows. We show that a surface-grafted polymer brush, 1-n-butyl-3-vinyl imidazolium bromide-based poly(ionic liquids), is able to reduce the interfacial friction by up to 66% and 42% in dodecane and water, resp. AFM-based force spectroscopy reveals that the polymer brush adopts distinctively different interfacial conformations: swollen in water but collapsed in dodecane. Minimal surface adhesion was observed with both polymer conformations, which can be attributed to steric repulsion as the result of a swollen conformation in water or surface solvation when the hydrophobic fraction of the polymer was exposed to the dodecane. The work brings addnl. insight on the polymer lubrication mechanism, which expands the possible design of the polymer architecture for interfacial lubrication and modification.

HPLC of Formula: 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary