Liu, Lei; Zhang, Wangqin; Xu, Chao; He, Jiaying; Xu, Zhenhui; Yang, Zehui; Ling, Fei; Zhong, Weihui published the artcile< Electrosynthesis of CF3-Substituted Polycyclic Quinazolinones via Cascade Trifluoromethylation/Cyclization of Unactivated Alkene>, HPLC of Formula: 20776-50-5, the main research area is alkenyl quinazolinone sodium triflinate electrochem tandem trifluoromethylation cyclization; trifluoroethyl fused quinazolinone preparation.
An atom and step economy cascade trifluoromethylation/cyclization of unactivated alkenes with Langlois reagent as a CF3 source was described. A variety of polycyclic quinazolinones were successfully synthesized in 52-81% yields under transition metal- and oxidant-free conditions. The Langlois reagent used in this strategy as a CF3 reagent possessed the advantages of bench-stablity, cost-effectivity and high-efficiency. Addnl., gram-scale reaction, broad substrate scope and good functional group tolerance demonstrated the synthetic usefulness of this protocol.
Advanced Synthesis & Catalysis published new progress about Electrochemical cyclization. 20776-50-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H6BrNO2, HPLC of Formula: 20776-50-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary