Chen, Xiang-Yu; Chen, Kun-Quan; Sun, De-Qun; Ye, Song published the artcile< N-Heterocyclic carbene-catalyzed oxidative [3+2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is spirocyclic oxindole lactone preparation; dioxindole enal oxidative annulation heterocyclic carbene catalyst.
The N-heterocyclic carbene-catalyzed oxidative [3+2] annulation of dioxindoles I (R = H, Bn; X = H, 4-Br, 5-H3CO, 6-Br) and enals R1CH=CHCHO (R1 = n-C6H13, HC=CHCH3, 4-FC6H4, etc.) was developed for giving the corresponding spirocyclic oxindole-γ-lactones II and III in good yields with high to excellent diastereo- and enantioselectivities. The challenging aliphatic enals worked effectively using this strategy. The oxidative cross coupling of homoenolate and enolate via single electron transfer was proposed as the key step for the reaction.
Chemical Science published new progress about Cross-coupling reaction, stereoselective. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary