Alam, Ryan M.; Keating, John J. published the artcile< An Expedient Approach to Pyrazolo[3,4-b]pyridine-3-carboxamides via Palladium-Catalyzed Aminocarbonylation>, Recommanded Product: 4-Bromobenzylamine, the main research area is iodo fluorobenzyl pyrazolopyridine formic acid amine palladium catalyst aminocarbonylation; fluorobenzyl pyrazolopyridine carboxamide preparation.
A series of novel 1,3-disubstituted pyrazolo[3,4- b]pyridine-3-carboxamide derivatives was prepared by introducing the 3-carboxamide moiety using palladium-catalyzed aminocarbonylation methodol. and employing CO gas generated ex-situ using a two-chamber reactor (COware ). The functional group tolerance of this optimized aminocarbonylation protocol was highlighted through the synthesis of a range of diversely substituted C-3 carboxamide pyrazolo[3,4- b]pyridines in excellent yields of up to 99%.
Synthesis published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary