Gopalaiah, Kovuru; Tiwari, Ankit; Choudhary, Renu; Mahiya, Kuldeep published the artcile< Straightforward Access to 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides and Quinazolines via Iron-Catalyzed Aerobic Oxidative Condensation of Amines>, Application In Synthesis of 3959-07-7, the main research area is aminobenzenesulfonamide primary amine iron catalyst oxidative cyclocondensation; dihydrobenzothiadiazine dioxide preparation; aminobenzylamine primary amine iron catalyst oxidative cyclocondensation; quinazoline preparation.
A novel and straightforward approach for constructing 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxides from 2-aminobenzenesulfonamide and benzylamines via oxidative condensation was explored. Abundant and cheap iron salt as a catalyst and air as an oxidant were employed, which makes the process more practical and economical. This reaction protocol was further applied to synthesize diverse functionalized quinazolines through oxidative condensation of 2-aminobenzylamines with benzylamines. Besides this, the use of amino acid such as phenylglycine as benzylamine surrogate was tested for the construction of 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide and quinazoline derivatives The proposed mechanistic pathway was validated by isolating the key intermediates.
ChemistrySelect published new progress about Benzothiadiazines Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Application In Synthesis of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary