Osyanin, V. A.; Korzhenko, K. S.; Rashchepkina, D. A.; Osipov, D. V.; Klimochkin, Yu. N. published the artcile< Nucleophilic Vinylic Substitution in Perfluoroacylchromenes. Diastereoselective Synthesis of Push-Pull Enamino Ketones>, Related Products of 3959-07-7, the main research area is enamino ketone diastereoselective preparation; perfluoroacylchromene nucleophilic vinylic substitution.
The reactions of 2-perfluoroacyl-1H-benzo[f]chromenes and 6,7-dimethyl-3-trifluoroacetyl-4H-chromene with primary aliphatic amines and ammonia afforded a series of enamino ketones containing a (2-hydroxynaphthalen-1-yl)methyl or 2-hydroxybenzyl substituent in the α-position with respect to the carbonyl group, e.g., I [R = H, cyclopropyl, Bn, etc.; X = CF3, C2F5, ]. These reactions involved opening of the pyran ring, which followed aza-Michael addition as the initial step. The obtained enamino ketones were found to exist in DMSO solution as single E isomers.
Russian Journal of Organic Chemistry published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Related Products of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary