Renzi, Polyssena; Azzi, Emanuele; Bessone, Enrico; Ghigo, Giovanni; Parisotto, Stefano; Pellegrino, Francesco; Deagostino, Annamaria published the artcile< Blue light enhanced Heck arylation at room temperature applied to allenes>, Product Details of C7H4BrF3, the main research area is tosyl alkdienylamine aryl bromide palladium catalyst Heck photochem arylation; arylvinyl tolylsulfonyl pyrrolidine preparation; aryl vinyl tolylsulfonyl piperidine preparation.
An unprecedented visible light enhanced room temperature Heck reaction between aryl halides and allenyl tosyl amines was here reported. A simple catalytic system (Pd(OAc)2/PPh3) was employed to afford arylated vinyl pyrrolidines and piperidines. A broad scope with high tolerance towards functional groups was observed Electronic effects play an important role in the efficiency of this process. Mechanistic studies, both exptl. and computational, indicated no evidence for a radical mechanism and a pivotal role of light in promoting the carbo-palladation step.
Organic Chemistry Frontiers published new progress about Allenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, Product Details of C7H4BrF3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary