Thorve, Pradip Ramdas; Maji, Biplab published the artcile< Aerobic primary and secondary amine oxidation cascade by a copper amine oxidase inspired catalyst>, Electric Literature of 3959-07-7, the main research area is quinazolinone preparation kinetic mechanistic study; amine aminobenzamide cascade aerobic oxidative coupling copper catalyst.
Herein, a bioinspired catalytic system for the one-pot cascade oxidation of a native primary amine and an in situ generated non-native secondary amine is reported. The catalyst consists of an o-quinone cofactor phd (1,10-phenanthroline-5,6-dione) and a copper ion and operates under ambient air conditions. Quinazolin-4(3H)-ones, which are common pharmacophores present in numerous pharmaceuticals and bioactive compounds, were synthesized in high yields. A detailed kinetic and mechanistic study elucidates the role of the catalyst in the multi-step oxidative cascade reaction.
Catalysis Science & Technology published new progress about Benzamides Role: RCT (Reactant), RACT (Reactant or Reagent) (amino). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Electric Literature of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary