In 2013,Bhadra, Sukalyan; Dzik, Wojciech I.; Goossen, Lukas J. published 《Synthesis of Aryl Ethers from Benzoates through Carboxylate-Directed C-H-Activating Alkoxylation with Concomitant Protodecarboxylation》.Angewandte Chemie, International Edition published the findings.Recommanded Product: 76006-33-2 The information in the text is summarized as follows:
A mixture of Ag2CO3 and Cu(OAc)2 catalyzed the ortho-alkoxylation and concomitant protodecarboxylation of potassium benzoates with trialkyl borates. Neither double alkoxylation nor nondecarboxylative alkoxylation was observed, confirming the high efficiency of the decarboxylation step following alkoxylation. The synthesis of the borate ester reagent can be combined with the decarboxylative alkoxylation in a one-pot procedure. The alc. is first treated with an equivalent amount of pinacol borane, and when gas evolution ceases, the carboxylate salt and catalyst are added and the decarboxylative coupling is performed. The experimental process involved the reaction of 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Recommanded Product: 76006-33-2)
3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. Recommanded Product: 76006-33-2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary