Cong, Zi-Song; Li, Yang-Guo; Du, Guang-Fen; Gu, Cheng-Zhi; Dai, Bin; He, Lin published the artcile< N-Heterocyclic carbene-catalyzed sulfa-Michael addition of enals>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is enal thiol sulfa Michael addition nitrogen heterocyclic carbene catalyst.
An efficient N-heterocyclic carbene (NHC) catalyzed sulfa-Michael addition (SMA) between enals and thiols has been developed. Under the catalysis of 10 mol% stable free carbene IPr and with 20 mol% hexafluoroisopropanol (HFIP) as an additive, enals react with a variety of thiols to afford the SMA adducts in 54-98% yields. In this process, the free carbene preferentially interacts with thiols through hydrogen-bonding and no NHC-catalyzed extended Umpolung transformations were observed
Chemical Communications (Cambridge, United Kingdom) published new progress about Michael reaction (sulfa). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary