Liang, Xiayu; Yu, Peng; Fu, Chen; Shen, Yongcun published the artcile< Organotin-catalyzed synthesis of hydroxyalkylamides from lactones via a ring-opening process>, Quality Control of 3959-07-7, the main research area is primary amine lactone dibutyltin acetate catalyst ring opening amidation; hydroxyalkylamide preparation.
A new strategy for the facile synthesis of hydroxyalkylamides through the ring-opening reaction of lactones with amine promoted by dibutyltin acetate was developed. A series of hydroxyalkylamide compounds were obtained and the method was successfully applied to the synthesis of pharmaceutically active mols. tyrosinase inhibitor V and HDAC inhibitor VI via a three-step synthetic pathway. The broad substrate scope, mild reaction conditions and practical application proved the effectiveness, compatibility and practicality of this method.
Tetrahedron Letters published new progress about Aliphatic alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary