《Manganese-Catalyzed β-Methylation of Alcohols by Methanol》 was written by Schlagbauer, Martin; Kallmeier, Fabian; Irrgang, Torsten; Kempe, Rhett. Electric Literature of C5BrMnO5 And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:
We report an earth-abundant-metal-catalyzed double and single methylation of alcs. A manganese catalyst, which operates at low catalyst loadings and short reaction times, mediates these reactions efficiently. A broad scope of primary and secondary alcs., including purely aliphatic examples, and 1,2-amino alcs. can be methylated. Furthermore, alc. methylation for the synthesis of pharmaceuticals has been demonstrated. The catalyst system tolerates many functional groups, among them hydrogenation-sensitive examples; and up-scaling is easily achieved. Mechanistic investigations are indicative of a borrowing hydrogen or hydrogen auto-transfer mechanism involving a bimetallic K-Mn catalyst. The catalyst accepts hydrogen as a proton and a hydride from alcs. efficiently and reacts with a chalcone via hydride transfer. After reading the article, we found that the author used Bromopentacarbonylmanganese(I)(cas: 14516-54-2Electric Literature of C5BrMnO5)
Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Electric Literature of C5BrMnO5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary