Xu, Zhihui; Yang, Tianbao; Tang, Niu; Ou, Yifeng; Yin, Shuang-Feng; Kambe, Nobuaki; Qiu, Renhua published the artcile< UV-Light-Induced N-Acylation of Amines with α-Diketones>, Synthetic Route of 3959-07-7, the main research area is amide preparation; amine alpha diketone photoinduced acylation.
Herein, a mild method for N-acylation of primary and secondary amines with α-diketones induced by UV light is reported. Forty-six examples with various functional groups are explored at room temperature with irradiation by three 26 W UV lamps (350-380 nm). The yield reaches 97%. The gram scale experiment product yield is 76%. Moreover, this system can be applied to the synthesis of several amino acid derivatives Mechanistic studies show that benzoin is generated in situ from benzil under UV irradiation
Organic Letters published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Synthetic Route of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary