Yokoyama, Akihiro; Ishii, Arisa; Ohishi, Tomoyuki; Kikkawa, Shoko; Azumaya, Isao published the artcile< Synthesis of a coronene analogue containing an amide bond by Pd-mediated intramolecular C-C bond formation of 2-halogenated 4-(alkylamino)benzoic acid cyclic trimer>, Quality Control of 16426-64-5, the main research area is coronene amide synthesis palladium mediated intramol cyclization.
A coronene analog containing amide linkage was synthesized from a halogenated cyclic triamide by palladium-mediated intramol. C-C bond formation (I → II). The cyclic triamide was formed from the condensation of 2-chloro-4-(isobutylamino)benzoic acid in the presence of dichlorotriphenylphosphorane in 1,1,2,2-tetrachloroethane. By contrast, the condensation of 2-bromo counterpart required silicon tetrachloride in pyridine. The intramol. C-C bond formation, which yielded the target coronene analog, occurred during the reaction of bromo-substituted cyclic triamide with palladium(II) acetate, triphenylphosphine, and potassium carbonate in N,N-dimethylformamide.
Tetrahedron Letters published new progress about Arylation (intramol.). 16426-64-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrNO4, Quality Control of 16426-64-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary