Zeynizadeh, Behzad; Mousavi, Hossein; Mohammad Aminzadeh, Farkhondeh published the artcile< A hassle-free and cost-effective transfer hydrogenation strategy for the chemoselective reduction of arylnitriles to primary amines through in situ-generated nickel (II) dihydride intermediate in water>, Synthetic Route of 3959-07-7, the main research area is benzonitrile reduction chemoseslective green chem; benzyl amine preparation.
A new, simple, efficient, inexpensive, and chemoselective transfer hydrogenation strategy was introduced for the straightforward reduction of arylnitriles to corresponding primary amines using sodium borohydride (NaBH4) and nickel acetate tetrahydrate (Ni(OAc)2•4H2O) through in situ-generated nickel (II) dihydride intermediate in the water medium at 50°. The presented methodol. featured moderate reaction conditions, nickel boride (Ni2B)-free trajectory, good-to-excellent yields of the products, relatively short reaction times, satisfactory chemoselectivity, and did not involve the use of toxic organic solvent and also any base or ligand.
Journal of Molecular Structure published new progress about Aromatic amides Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Synthetic Route of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary