In 2009,Chemistry – A European Journal included an article by Andaloussi, Mounir; Lindh, Jonas; Saevmarker, Jonas; Sjoeberg, Per J. R.; Larhed, Mats. COA of Formula: C6H4BBrF3K. The article was titled 《Microwave-Promoted Palladium(II)-Catalyzed C-P Bond Formation by Using Arylboronic Acids or Aryltrifluoroborates》. The information in the text is summarized as follows:
The first PdII-catalyzed P arylation has been performed by using palladium acetate, the rigid bidentate ligand dmphen (dmphen = 2,9-dimethyl-1,10-phenanthroline), and without the addition of base or acid. Couplings of arylboronic acids or aryl trifluoroborates with H-phosphonate dialkyl esters were conducted in 30 min with controlled microwave (MW) heating under non-inert conditions. Aryl phosphites were also synthesized at room temperature with atm. air as the sole reoxidant. The arylated phosphonates were isolated in 44-90% yields. The excellent chemoselectivity of the method was illustrated in the synthesis of a Mycobacterium tuberculosis glutamine synthetase (MTB-GS) inhibitor. Online ESI-MS was used to detect cationic palladium species in ongoing reactions directly, and a catalytic cycle has been proposed based on these results. In the experiment, the researchers used many compounds, for example, potassium (3-bromophenyl)trifluoroborate(cas: 374564-34-8COA of Formula: C6H4BBrF3K)
potassium (3-bromophenyl)trifluoroborate(cas: 374564-34-8) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C6H4BBrF3K Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary