In 2018,Advanced Synthesis & Catalysis included an article by Han, Wen-Jing; Pu, Fan; Li, Chao-Jun; Liu, Zhong-Wen; Fan, Juan; Shi, Xian-Ying. SDS of cas: 76006-33-2. The article was titled 《Carboxyl-Directed Conjugate Addition of C-H Bonds to α,β-Unsaturated Ketones in Air and Water》. The information in the text is summarized as follows:
A simple ruthenium-catalyzed conjugate addition of C-H bonds to α,β-unsaturated ketones directed by a removable carboxyl group was developed as an effective protocol to synthesize ortho-alkylated benzoic acids in a greener manner. Without any additives, satisfactory to excellent yields of the targeted products were achieved in neat water, and the process characterizes in mild reaction conditions (in air and water), simple operations, and broad substrate scope. Noteworthy features of this method include mild reaction conditions (in air and water), operational simplicity and broad substrate scope. The versatility and utility of the addition products were demonstrated through further transformation into commonly inaccessible but highly useful motifs of meta-substituted alkylbenzenes and 3-substituted isochromanones. The results came from multiple reactions, including the reaction of 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2SDS of cas: 76006-33-2)
3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. SDS of cas: 76006-33-2Some of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary