Organic compounds having carbon bonded to bromine are called organic bromides. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application In Synthesis of 5445-17-0.
Hu, Chaolei;Xu, Wenjing;Conrads, Christian Martin;Wu, Jingnan;Pich, Andrij research published 《 Visible light and temperature dual-responsive microgels by crosslinking of spiropyran modified prepolymers》, the research content is summarized as follows. Light-responsive microgels are interesting colloidal systems with potential applications in the biotechnol. and medicine. However, synthesis of light-responsive microgels with high loading of photoswitchable mols. is still very challenging. Herein we developed a new method to synthesize light and temperature dual-responsive spiropyran-modified poly(N-vinylcaprolactam) microgels. The novel and straightforward microgels synthesis route involved: a) synthesis of poly(N-vinylcaprolactam-co-vinylformamide) copolymers via RAFT polymerization followed by the hydrolysis to obtain primary amine groups, b) attachment of carboxyl-modified spiropyran mols. to polymer chains via coupling, and c) crosslinking of spiropyran-modified polymer chains in W/O miniemulsion to form microgels. Via this method, we successfully synthesized poly(N-vinylcaprolactam) microgels containing more than 10 mol% spiropyran. The reversible light responsiveness of the spiropyran-modified copolymers and microgels in aqueous solution, which originates from the spiropyran photoisomerization under irradiation with different wavelengths, was demonstrated by UV-Vis spectroscopy. Spiropyran-modified copolymers demonstrate shift of the lower critical solution temperature (LCST) due to the polarity change of spiropyran mols. under dark, UV and visible light. Surprisingly, dynamic light scattering (DLS) results show that the microgels based on the same copolymers are less affected by UV irradiation Microgels are swollen in darkness when spiropyran mols. are in the polar, merocyanine form, and collapse after irradiation with visible light, due to the transformation of spiropyran to the relatively nonpolar, closed spirocyclic form. In addition, the spiropyran-modified microgels exhibit reversible temperature responsiveness by presenting a volume phase transition in water from a swollen state to a collapsed state with increasing temperature and the transition temperature decreased compared to the pristine microgels due to the hydrophobicity of spiropyran units.
Application In Synthesis of 5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary