Hu, Jiyong team published research in Polyhedron in 2022 | 1575-37-7

Recommanded Product: 4-Bromobenzene-1,2-diamine, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 4-Bromobenzene-1,2-diamine.

Hu, Jiyong;Chao, Tingting;Yuan, Bangpeng;Guo, Yan;Zhang, Junshuai;Zhao, Jin′an;Zhao, Xuemin;Hou, Hongwei research published ã€?Benzimidazole-quinoline-based copper complexes: Exploration for their possible antitumor mechanismã€? the research content is summarized as follows. In this study, we synthesized and characterised two benzimidazole-quinoline-based copper complexes, namely, [Cu(btmbq)Br]2 (1) and [Cu(btmbq)Cl]2 (2), (btmbq = 3-(1-(1H-benzotriazol-1-y-l)methyl)-6-bromo-1H-benzoimidazol-2-yl)isoquinoline). Both complexes showed strong antitumor abilities against the colon cancer cell line (HCT116) and low cytotoxicity against the normal liver cell line (L-02). The DNA binding affinity was evaluated using CD and fluorescence spectroscopy, and the Ksv and Kapp values were further quantified, revealing that the complexes bound to DNA in the intercalation mode, and caused oxidative damage to pBR322 DNA. Furthermore, complex 1 interfered with the steady-state balance of redox and Ca2+ in HCT116 cells, as well as induced cell mitochondrial membrane potential (Δψm) collapse, ATP dissipation, ultimately arrested the cell cycle in G2 phase and induced cell apoptosis. Further exploration demonstrated that the production of reactive oxygen species (ROS) might be the major contributors to the apoptotic death of HCT116 cells.

Recommanded Product: 4-Bromobenzene-1,2-diamine, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary