Organic compounds having carbon bonded to bromine are called organic bromides. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. HPLC of Formula: 629-04-9.
Izmestâ²ev, Alexei N.;Anikina, Lada V.;Zanin, Igor E.;Kolotyrkina, Natalya G.;Izmalkova, Ekaterina S.;Kravchenko, Angelina N.;Gazieva, Galina A. research published ã?Design, synthesis and in vitro evaluation of the hybrids of oxindolylidene and imidazothiazolotriazine as efficient antiproliferative agentsã? the research content is summarized as follows. 1,3-Diethyl-6-oxindolylidenetetrahydroimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-2,7-dione with a 2-Pr substituent at the nitrogen atom of the oxindole fragment (1d) was identified previously as a lead compound in an effort to discover antiproliferative agents based on oxindolylidene derivatives of imidazothiazolotriazine. A broadened structural optimization using an earlier developed efficient synthetic route provided 17 new oxindolylidene imidazothiazolotriazines which displayed evident antiproliferative activity in cellular assays (GI50 0.60-8.37 μM). The most potent compounds 5d-s (GI50 < 4.5 μM) contained the 1,3-diethyltetrahydroimidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazine core and an alkyl substituent at the nitrogen atom of the oxindole fragment. Compound 5m with an amyl substituent at the nitrogen atom of the oxindole fragment possessed higher antiproliferative activity with mean growth of 60 cancer cell lines -20.22%, and average values of GI50 1.45 and TGI 3.43 μM. Compound 5m was not toxic against the normal Madin-Darby canine kidney MDCK-M cell line (IC50 > 100 μM). The IC50 value of compound 5m against normal human embryonic kidney cells HEK293 was 17.65 μM, which appeared to be 3-fold higher than the IC50 value of 5m against rhabdomyosarcoma cells.
629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., HPLC of Formula: 629-04-9
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary