Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Quality Control of 629-04-9.
Kaur, Komalpreet;Utreja, Divya;Dhillon, Narpinderjeet K.;Pathak, Rajesh K.;Singh, Kamaljit research published 《 N-alkyl isatin derivatives: Synthesis, nematicidal evaluation and protein target identifications for their mode of action》, the research content is summarized as follows. Meloidogyne incognita is an economically dominant pathogen infesting a wide range of crops curbing their growth and productivity. Deregistration of frontline nematicides has necessitated exploration of innovative and novel class of structurally diverse nematicides with streamlined activity. In this context, N-alkylated derivatives of isatin known for their remarkable biol. profile were synthesized, characterized and evaluated in vitro for their antinemic character followed by in silico studies for their mode of action and toxicol. studies for their fitness as agrochem. The antinemic evaluation was carried by egg hatch inhibition and juvenile mortality and its effect on egg hatching. Compounds 1 and 2a exhibited nematicidal potential and significantly decreased egg hatching and increased juvenile mortality. For egg hatch inhibition LC50 and LC95 values for 1 were found to be 0.125 and 1.380 mg/mL and for compound 2a, 0.457 and 8.511 mg/mL resp. For juvenile mortality LC50 and LC95 values for 1 were found to be 0.109 and 0.776 mg/mL and for 2a, 0.190 and 1.380 mg/mL resp. For insights into the mode of action of the synthesized mols., in silico studies for the targeted effects were conducted which revealed novel interaction with pathogenic protein – Aspartyl protease. Computational studies on the drug-ability and potential toxicity of the selected compounds revealed they belonged to class IV and are safe. With good reasons, our compounds hold value for their exploration in agrochem. industry and thus, this study identifies a new scaffold with useful level of nematicidal activity for its use in agriculture industry.
Quality Control of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary