Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 402-49-3.
Lavinda, Olga;Witt, Collin H.;Woerpel, K. A. research published 《 Origin of High Diastereoselectivity in Reactions of Seven-Membered-Ring Enolates》, the research content is summarized as follows. Unlike many reactions of their six-membered-ring counterparts, the reactions of chiral seven-membered-ring enolates e.g., 5-(tert-Butyl)-1-methylazepan-1-one are highly diastereoselective. Diastereoselectivity was observed for a range of substrates, including lactam, lactone, and cyclic ketone derivatives The stereoselectivity arises from torsional and steric interactions that develop when electrophiles approach the diastereotopic π-faces of the enolates, which are distinguished by subtle differences in the orientation of nearby atoms of the ring.
402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., Electric Literature of 402-49-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary