One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate, Safety of Methyl 2-bromopropanoate
Li, Dengke;Shen, Xianfu research published 《 Iron-catalyzed regioselective alkylation of 1,4-quinones and coumarins with functionalized alkyl bromides》, the research content is summarized as follows. A simple and efficient method was developed for the synthesis of alkyl-quinone/coumarin derivatives, e.g., I and II [R = H, 6-Me, 7-OMe, etc.; R1 = CH(Me)2CO2Et, Bn, 4-MeC6H4CH2, etc.] via Fe-catalyzed regioselective alkylation of 1,4-quinones and coumarins, using functionalized alkyl bromides as alkylating reagents. The reaction proceeded under mild conditions with the addition of alkyl bromides to a wide range of 1,4-quinone and coumarin derivatives with a broad substrate scope and wide functional group tolerance to provide the products in good yields. Further application of these strategies could be extended to important biol. active antimalarial lead drugs on a gram scale in a single step for medicinal purposes.
5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Safety of Methyl 2-bromopropanoate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary