Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 4224-70-8.
Li, Jianbin;Huang, Chia-Yu;Han, Jing-Tan;Li, Chao-Jun research published 《 Development of a quinolinium/cobaloxime dual photocatalytic system for oxidative C-C cross-couplings via H2 release》, the research content is summarized as follows. Designing mol. photocatalysts for potent photochem. reactivities ranks among the most challenging but rewarding endeavors in synthetic photochem. Herein, we document a quinoline-based organo-photoredox catalyst, 2,4-bis(4-methoxyphenyl)quinoline (DPQN2,4-di-OMe), that could be assembled via the facile aldehyde-alkyne-amine (A3) couplings. Unlike the reported photocatalysts, which impart their photoreactivities as covalently linked entities, our mechanistic studies suggested a distinct proton activation mode of DPQN2,4-di-OMe. Simply upon protonation, DPQN2,4-di-OMe could reach a highly oxidizing excited state under visible-light irradiation (E*1/2 = +1.96 V vs a standard calomel electrode, SCE). On this basis, the synergistic merger of DPQN2,4-di-OMe and cobaloxime formulated an oxidative cross-coupling platform, enabling the Minisci alkylation and various C-C bond-forming reactions with a diverse pool of radical precursors in the absence of chem. oxidants. The catalytic loading of DPQN2,4-di-OMe could be minimized to 0.025 mol % (TON = 3360), and a polymer-supported photocatalyst, DPQN2,4-di-OR@PS, was prepared to facilitate catalyst recycling (at a 0.50 mmol % loading and up to five times without significant loss of photosynthetic efficiency).
Synthetic Route of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary