A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Recommanded Product: Ethyl 3-bromo-2-oxopropanoate.
Mashal, Neda;Azizian, Javad;Larijani, Kambiz;Nematollahi, Fereshteh;Azizian, Homa research published 《 Baker′s Yeast Promoted One-Pot Synthesis of New 1,2,4-Triazolpyrimido-1,3,4-Oxadiazoles: Investigation of Antioxidant and Antimicrobial Activity》, the research content is summarized as follows. In this study, baker′s yeast promoted one-pot synthesize of new 1,2,4-triazolpyrimidooxadiazole derivatives I (R = C(O)2Et, Ph, 4-methylphenyl, 4-methoxyphenyl, 4-nitrophenyl; R1 = R2 = Ph, 4-methylphenyl, 4-methoxyphenyl; X = H, Me, NO2) in high yields using multicomponent reactions of isatins II, guanidine, alkyl bromides RC(O)CH2Br, acetaldehyde and hydrazonoyl chlorides R1C(Cl)=NNHR2 in the presence of baker′s yeast as a high performance catalyst in water at room temperature Investigation of antioxidant ability of synthesized compounds using radical trapping of diphenyl-picrylhydrazine (DPPH)and ferric reduction power experiment is another purpose in this research. Also, the antimicrobial activity of some synthesized compounds proved by employing the disk diffusion test on Gram-pos. and Gram-neg. bacteria. This procedure has some benefits such as short reaction time, product with excellent yields and simple, efficient, inexpensive, and environment-friendly catalyst.
Recommanded Product: Ethyl 3-bromo-2-oxopropanoate, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.
Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.
Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary