Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. COA of Formula: C7H6Br2.
Mirzazadeh, Roghieh;Asgari, Mohammad S.;Barzegari, Ebrahim;Pedrood, Keyvan;Mohammadi-Khanaposhtani, Maryam;Sherafati, Maedeh;Larijani, Bagher;Rastegar, Hossein;Rahmani, Hojjat;Mahdavi, Mohammad;Taslimi, Parham;Uc, Eda M.;Gulcin, Ilhami research published 《 New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies》, the research content is summarized as follows. A new series of quinoxalin-1,3,4-oxadiazole derivatives I [R = H, 4-F, 2-Br, etc.] was synthesized and evaluated against some metabolic enzymes including human carbonic anhydrase (hCA) isoenzymes I and II (carbonic anhydrases I and II), cholinesterase (acetylcholinesterase and butyrylcholinesterase), and α-glucosidase. Obtained data revealed that all the synthesized compounds were more potent as compared with the used standard inhibitors against studied target enzymes. Among the synthesized compound I [R = 4-F] against hCA I, compound I [R = 4-Cl] against hCA II, compound I [R = 3-F] against acetylcholinesterase and butyrylcholinesterase and compound I [R = 3-Br] against α-glucosidase were the most potent compounds with inhibitory activity around 1.8- to 7.37-fold better than standard inhibitors. Furthermore, docking studies of these compounds were performed at the active site of their target enzymes.
COA of Formula: C7H6Br2, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.
3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.
3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary