A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Recommanded Product: Methyl 2-bromopropanoate.
Peng, Chuan-Chong;Wu, Li-Jun;Pi, Shao-Feng research published 《 Palladium-catalyzed difunctionalization/dearomatization of N-benzylacrylamides with α-carbonyl alkyl bromides: facile access to azaspirocyclohexadienones》, the research content is summarized as follows. An efficient palladium-catalyzed difunctionalization/dearomatization of N-benzylacrylamides with α-carbonyl alkyl bromides as alkyl radical precursors was described. Various α-carbonyl alkyl bromides, including α-bromoalkyl esters and ketones, reacted smoothly to provide important azaspirocyclohexadienones I [R1 = H, Me, Et, etc.; R2 = H, Me; R3 = H, Me, Cl; R4 = t-Bu, cyclopropyl, cyclohexyl, etc.; R5 = H, Me; X = COOMe, COOEt, COPh, etc.] in moderate to excellent yields. In addition, mechanistic studies suggested that the reaction proceeded via a radical pathway.
Recommanded Product: Methyl 2-bromopropanoate, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary