Organic compounds having carbon bonded to bromine are called organic bromides. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C8H6BrF3.
Pothireddy, Mohanreddy;Hazra, Gurupada;Babu, Penke Vijaya;Thirupathi, Barla;Dandela, Rambabu research published 《 Synthesis of Fluorinated 2-Benzylphthalazin-1(2 H )-one, 1-Phthalazinamine, and 1-Alkoxy/Benzyloxyphthalazine Derivatives by an Ultrasonication Method》, the research content is summarized as follows. Fluorinated heterocyclic compounds have been proven to exhibit interesting potential biol. activities. Therefore, various fluorinated 2-benzylphthalazine-1(2 H)-one and phthalazine-1-amine derivatives and nonfluorinated 1-alkoxy/benzyloxyphthalazines derivatives have been synthesized by an ultrasonication method. This protocol is more efficient than the conventional method in terms of its product yield and reaction handling and timelines.
Application of C8H6BrF3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., 402-49-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary