Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 402-49-3.
Ren, Peng;Li, Qinglin;Song, Tao;Wang, Zhaozhan;Motokura, Ken;Yang, Yong research published 《 Highly Efficient and Stable Atomically Dispersed Cu Catalyst for Azide-Alkyne Cycloaddition Reaction》, the research content is summarized as follows. In this study, a highly stable and efficient single-atom Cu dispersed on N-doped porous carbon as a superior catalyst for azide-alkyne cycloaddition reaction is reported. A broad set of 1,4-disubstituted 1,2,3-triazoles was synthesized in high to excellent yields with good tolerance of various functional groups in a cost-effective, environmentally-friendly manner. Parallel studies show that the single-atom Cu with unique coordination structure exhibits superior catalytic activity to the metallic Cu nanoparticles analog. Remarkably, the single-atom Cu catalyst demonstrates robust stability and can be reused several times without variations in activity and regioselectivity.
402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., Synthetic Route of 402-49-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary