Month: October 2022

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Computed Properties of 6911-87-1.

Fan, Xu;Liu, Hui;Ma, Shidi;Wang, Feng;Yang, Jinhui;Li, Dianjun research published 《 Visible light-induced PPh₂Cy/CsI-promoted cascade radical decarboxylative/cyclization of redox-active esters with acrylamides》, the research content is summarized as follows. A visible-light-induced PPh₂Cy/CsI-promoted tandem radical decarboxylative/alkylarylation of alkyl substituted redox-active esters I (R = t-Bu, cyclohexyl, cyclopentyl, etc.) and N-acrylamides 2-R⁵-3-R⁴-4-R²-5-R³C₆HN(R¹)C(O)C(=CH₂)CH₃ (R¹ = H, Me, Ph, etc.; R² = H, Cl, Br, Me; R³ = H, Me; R⁴ = H, Me; R⁵ = H, Cl, Me, F; R⁴R⁵ = -CH=CH-CH=CH-) or N-methyl-N-(2-methylprop-2-enoyl)benzamides 2-R⁹-3-R⁸-4-R⁷-5-R⁶C₆HC(O)N(Me)C(O)C(=CH₂)Me (R⁶ = H, Me; R⁷ = H, Cl, F, MeO; R⁸ = H, Me; R⁹ = H; R⁸R⁹ = -CH=CH-CH=CH-) to generate 3,3-dialkyl substituted oxindoles II and isoquinoline-1,3-diones derivatives III was developed under metal-free conditions. This transformation provides an alternative and mild method for the synthesis of highly functionalized five- 3,3-dialkyl substituted oxindoles and isoquinoline-1,3-diones derivatives

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Computed Properties of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Quality Control of 70-23-5

Fan, Tingting;Guo, Weikai;Shao, Ting;Zhou, Wenbo;Hu, Pan;Liu, Mingyao;Chen, Yihua;Yi, Zhengfang research published 《 Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane》, the research content is summarized as follows. A series of phenylthiazole and phenylthiophene pyrimidindiamine derivatives l [R¹ = ethylamino, propylamino, butylamino, pyrrolidino; R² = H, OMe, F, Cl, Br, etc.] were designed and synthesized by modifying the hit compound (N²-isobutyl-N4-((4-methyl-2-phenylthiazol-5-yl)methyl) pyrimidine-2,4-diamine) and their antibacterial activities were evaluated both in-vitro and in-vivo was reported. Among the tested compounds, compound I [R¹ = isobutylamino; R² = 3-bromo] displayed the best antibacterial activities, which was not only capable of inhibiting E. coli and S. aureus growth at concentrations as low as 2 and 3μg/mL in-vitro, but also efficacious in a mice model of bacteremia in vivo. Unlike conventional antibiotics, compound I [R¹ = isobutylamino; R² = 3-bromo] was elucidated to mainly destroy the bacterial cell membrane, with the dissipation of membrane potential and leakage of contents, ultimately leading to cell death. The destruction of cell structure was challenging to induce bacterial resistance, which suggested that compound I [R¹ = isobutylamino; R² = 3-bromo] was a promising alternatives to antibiotics against bacteria.

Quality Control of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid, Application of C6H6BBrO2

Fan, Lingling;Luo, Zhongfu;Li, Yi;Liu, Xinyun;Fan, Judi;Xue, Wei;Tang, Lei;Li, Yong research published 《 Synthesis and antifungal activity of imidazo[1,2-b]pyridazine derivatives against phytopathogenic fungi》, the research content is summarized as follows. A series of 3,6-disubstituted imidazo[1,2-b]pyridazine derivatives were synthesized and characterized with spectroscopic analyses. The antifungal activities of these compounds against nine phytopathogenic fungi were evaluated by the mycelium growth rate method. The in vitro antifungal bioassays indicated that most of compounds displayed excellent and broad-spectrum antifungal activities. Especially, compounds 6-chloro-3-phenylimidazo[1,2-b]pyridazine, 6-chloro-3-(2-fluorophenyl)imidazo[1,2-b]pyridazine, 6-chloro-3-(2-chlorophenyl)imidazo[1,2-b]pyridazine, 6-chloro-3-(thiophen-3-yl)imidazo[1,2-b]pyridazine and 6-methoxy-3-phenylimidazo[1,2-b]pyridazine exhibited 1.9-25.5 fold more potent than the com. available fungicide hymexazol against Corn Curvalaria Leaf Spot (CL), Alternaria alternate (AA), Pyricularia oryzae (PO) and Alternaria brassicae (AB) strains. Structure-activity relation anal. showed that the enhanced antifungal activity is significantly affected by the substituents on the benzene ring and pyridazine ring.

Application of C6H6BBrO2, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Organic compounds having carbon bonded to bromine are called organic bromides. Product Details of C7H8BrN.

Fan, Jiali;Wei, Qiancheng;Zhu, Ershu;Gao, Jing;Cheng, Xiamin;Lu, Yongna;Loh, Teck-Peng research published 《 Visible light-induced mono-bromination of arenes with BrCCl₃》, the research content is summarized as follows. A highly efficient and regioselective bromination of electron-rich arenes and heteroarenes using com. available BrCCl₃ as a “Br” source has been developed. The reaction was performed in air under mild conditions with photocatalyst Ru(bpy)₃Cl₂·6H₂O, avoiding the usage of strong acids and strong oxidants. Mono-brominated products were obtained with medium to excellent yields (up to 94%). This strategy has shown good compatibility and high para-selectivity, which will facilitate the complicated synthesis.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Product Details of C7H8BrN

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Quality Control of 244205-40-1.

Fan, Chi-Hang;Xu, Tianyue;Ke, Zhihai;Yeung, Ying-Yeung research published 《 Autocatalytic aerobic ipso-hydroxylation of arylboronic acid with Hantzsch ester and Hantzsch pyridine》, the research content is summarized as follows. Hantzsch esters were very useful hydrogen and electron donors that was applied in many reactions. After the reactions, aromatic Hantzsch pyridines are generated as the byproducts and their roles were commonly ignored. Herein, the use of Hantzsch pyridine as a promoter to activate Hantzsch ester in the generation of the hydrogen peroxy radical, which is useful for the ipso-hydroxylation of arylboronic acids to give phenols was reported. The reaction does not require an external catalyst or light. The conditions were mild and highly compatible with different functional groups.

Quality Control of 244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Electric Literature of 5445-17-0.

Fan, Bo;Wan, Jing;McKay, Alasdair;Qu, Zhenyuan;Thang, San H. research published 《 Facile synthesis of well-controlled poly(1-vinyl imidazole) by the RAFT process》, the research content is summarized as follows. Poly(vinyl imidazole)s, which contain heterocyclic aromatic rings on the polymer side chains, are of increasing interest for a wide variety of applications ranging from catalysis, polymeric ionic liquids to membrane material. However, the controlled radical polymerization of vinyl imidazoles, including 1-vinyl imidazole (1VIM), 2-vinyl imidazole (2VIM) and 4-vinyl imidazole (4VIM), proved to be extremely challenging in the past decades. Here, we demonstrate, for the first time, that well-controlled and low dispersity (D as low as 1.05) poly(1VIM) could be synthesized via RAFT polymerization by using acetic acid as a special solvent. Acetic acid not only works as a solvent that allows homogeneous polymerization, it also protonates 1VIM, thereby, allowing the stabilization of propagating radicals during polymerization To verify the efficacy of the RAFT polymerization of 1VIM in acetic acid, various polymerization parameters including different RAFT agents, initiator and monomer concentrations, temperatures, etc. had been examined Moreover, detailed kinetic studies revealed a linear, pseudo-first-order polymerization behavior of 1VIM in acetic acid, and the apparent rate constants were calculated Furthermore, the living characteristic of this RAFT process was demonstrated by chain extension with Bu acrylate (nBA) and N,N-di-Me acrylamide (DMA) to form resp. block copolymers with low dispersities. Overall, the synthesis of well-controlled poly(1VIM) is expected to greatly expand the design and utility of vinyl imidazole-based materials and their applications in catalysis, membrane material, heavy metal removal, fuel cells and many other fields.

Electric Literature of 5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application of C9H9BrO3.

Fadeeva, Anastasia A.;Ioffe, Sema L.;Tabolin, Andrey A. research published 《 Chlorination of Conjugated Nitroalkenes with PhICl₂ and SO₂ Cl₂ for the Synthesis of α-Chloronitroalkenes》, the research content is summarized as follows. Chlorination of conjugated nitroalkenes with iodobenzene dichloride or sulfuryl chloride to give target α-chloronitroalkenes in good yields was described. Details of the procedure depend on the donating ability of the nitroalkene substituents. The activity of the described chlorinating agents increases in order ‘PhICl₂/Py’ < ‘SO₂Cl₂‘ < ‘SO₂Cl₂/HCl’ with the former produced the best yields for highly donating substrates and the latter for non-activated groups. An autocatalytic role of hydrogen chloride and the chemoselectivity of chlorination were also demonstrated.

Application of C9H9BrO3, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde, Category: bromides-buliding-blocks

Fadeev, Alexander A.;Makarov, Anton S.;Ivanova, Olga A.;Uchuskin, Maxim G.;Trushkov, Igor V. research published 《 Extended Corey-Chaykovsky reactions: transformation of 2-hydroxychalcones to benzannulated 2,8-dioxabicyclo[3.2.1]octanes and 2,3-dihydrobenzofurans》, the research content is summarized as follows. The divergent synthesis of benzannulated 2,8-dioxabicyclo[3.2.1]octanes I [R¹ = H, 4-NO₂, 4-Cl, etc.; R² = Ph, 4-MeC₆H₄, 4-FC₆H₄, etc.] and 2,3-dihydrobenzofurans II [X= H, 4-NO₂, 4-Cl, etc.; R¹ = Ph, 4-MeC₆H₄, 4-FC₆H₄, etc.] using the concept of extended Corey-Chaykovsky reactions was reported. With this concept, 2-hydroxychalcones were treated with the Corey ylide providing highly reactive donor-acceptor cyclopropanes that were introduced in a one pot manner for further transformations. We demonstrated that the nucleophilic three-membered ring opening followed by cyclization under mild reaction conditions afforded the 2,8-dioxabicyclo[3.2.1]octane scaffold. On the other hand, heating the intermediates with a strong Bronsted acid furnished 2-phenacyl-2,3-dihydrobenzofurans. These transformations, resulting in products with crucially different heterocyclic skeletons from the same starting compounds, demonstrate the enormous potential of the extended Corey-Chaykovsky reaction.

Category: bromides-buliding-blocks, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Product Details of C5H7BrO3

Ezzatzadeh, Elham;Hargalani, Fariba Zamani;Shafaei, Faezeh research published 《 Bio-Fe₃O₄-MNPs Promoted Green Synthesis of Pyrido[2,1-a]isoquinolines and Pyrido[1,2-a]quinolines: Study of Antioxidant and Antimicrobial Activity》, the research content is summarized as follows. In this work, synthesis of pyrido[2,1-a]isoquinolines and pyrido[1,2-a]quinolines in excellent yield using multicomponent reaction of isoquinoline, Me malonyl chloride, alkyl bromides, and triphenylphosphine in the presence of catalytic amount of Fe₃O₄-MNPs in water at 80° were investigated. The reduction of ferric chloride solution with Clover Leaf water extract resulted in the synthesis of magnetic iron oxide nanoparticles (Fe₃O₄-NPs) as a green method. The antioxidant activity was studied for some newly synthesized compounds using the DPPH radical trapping and ferric ion reduction experiments and results were compared with synthetic antioxidants (TBHQ and BHT). These compounds showed trace DPPH radical trapping and excellent reducing strength of ferric ion. The antimicrobial activity of some synthesized compounds was studied employing the disk diffusion test on Gram-pos. bacteria and Gram-neg. bacteria. The results of disk diffusion test showed that these compounds prevented the bacterial growth.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Product Details of C5H7BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Reference of 2576-47-8.

Esmaeili, Abbas Ali;Mesbah, Fariba;Moradi, Abbas;Khojastehnezhad, Amir;Khalili, Maryam research published 《 Straightforward and simple synthesis of novel pyranodipyrimidine derivatives via reaction of aromatic aldehydes and heterocyclic-1,3-dicarbonyl compound》, the research content is summarized as follows. An efficient and simple procedure was described for the synthesis of a novel series of polycyclic compounds containing pyranodipyrimidine core I [Ar = Ph, 2-ClC₆H₄, 1-naphthyl, etc.] via cyclocondensation reaction of 2,3-dihydro-thiazolo[3,2-a]pyrimidine-5,7-dione and aromatic aldehyde derivatives in the presence of diisopropylethylamine as an organo-base catalyst. This procedure gave the desired products in high yields.

Reference of 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary