Month: October 2022

Organic compounds having carbon bonded to bromine are called organic bromides. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. HPLC of Formula: 2576-47-8.

Schaffer, Andreas;Kraenzlein, Moritz;Rieger, Bernhard research published 《 Synthesis and Application of Functional Group-Bearing Pyridyl-Based Initiators in Rare Earth Metal-Mediated Group Transfer Polymerization》, the research content is summarized as follows. The polymer class of poly(vinylphosphonates) offers a wide array of attractive features such as high biocompatibility, thermoresponsive behavior, and the option for the directed introduction of small mols. at the initial step of the polymerization Through the latter, polymer conjugates consisting of targeting ligands, fluorophores, or pharmacol. active substances become feasible. However, the modification of such compounds for the utilization in postpolymn. functionalization is usually cumbersome due to their structural complexity. In this study, we considered this factor and envisioned a flexible platform of functional polymers via the introduction of initiators comprising reactive functionalities. Hence, a series of customized initiators with protected functional groups (O-tert-butyldimethylsilyl, 2,5-dimethylpyrrole, and STrityl) were synthesized and studied in the C-H bond activation with Cp₂Y(CH₂TMS)(THF). The pos. outcome of the activation experiments allowed the use of these initiators in the rare earth metal-mediated group transfer polymerization (REM-GTP). The versatility of this approach was demonstrated by end-group anal. using electrospray ionization mass spectrometry (ESI-MS) and DOSY-NMR, confirming the incorporation of the individual end group in poly(di-Et vinylphosphonate) (PDEVP). On this basis, PDEVP with varying feed concentrations was generated and the protection groups were removed to release the reactive motif. Doing so eventually enabled the successful coupling of model compounds, namely, cholesteryl chloroformate and N-Ph maleimide, which established a foundation in the direction of more sophisticated polymer conjugates involving complex and highly functional compounds

HPLC of Formula: 2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline, SDS of cas: 6911-87-1

Scattolin, Thomas;Gharbaoui, Tawfik;Chen, Cheng-yi research published 《 A Nucleophilic Deprotection of Carbamate Mediated by 2-Mercaptoethanol》, the research content is summarized as follows. Carbamates, typically used for the protection of amines, including Cbz, Alloc, and Me carbamate, was readily deprotected by treatment with 2-mercaptoethanol in the presence of potassium phosphate tribasic in N,N-dimethylacetamide at 75°C. This nucleophilic deprotection protocol was superior to the standard hydrogenolysis or Lewis acid-mediated deprotection conditions for substrates bearing a functionality sensitive to these more traditional methods.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., SDS of cas: 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Recommanded Product: Ethyl 3-bromo-2-oxopropanoate

Savari, Mehdi;Varasteh-Moradi, Ali;Sayyed-Alangi, S. Zahra;Hossaini, Zinatossadat;Mehrabian, Ramin Zafar research published 《 Green novel multicomponent synthesis and biological evaluation of new oxazolopyrazoloazepines and reduction of nitrophenols in the presence of Ag/Fe₃O₄/ZnO@MWCNT MNCs》, the research content is summarized as follows. In this research, new derivatives of oxazolopyrazoloazepines I (X = H, Me, Cl, NO₂; R = H, COOMe, COOEt; R¹ = Me, Et; R² = 4-methoxyphenyl, 4-methylphenyl, COOEt, 4-nitrophenyl) were synthesized in high yields using multicomponent reaction of anilines 4-XC₆H₄NH₂, oxalylchloride, alkyl bromides BrCH₂C(O)R², activated acetylenic compounds RCCC(O)OR¹, hydrazine and Et bromopyruvate in the presence of Ag/Fe₃O₄/ZnO@MWCNT magnetic nanocomposite (MNCs) as a high-performance magnetic catalyst in ionic liquid at room temperature The Ag/Fe₃O₄/ZnO@MWCNT magnetic nanocomposites (MNCs) were synthesized using 1-octyl-3-Me imidazolium bromide ([OMIM]Br) as a stabilizer and soft template. Also, the catalytic activity of the Ag/Fe₃O₄/ZnO@MWCNT MNCs was evaluated in reduction of organic pollutants such as 4-nitrophenol (4-NP) in water at mild conditions. The results indicated that the biosynthesized nanocomposites (NCs) have high catalytic activity for organic pollutants within few seconds. Because of having benzazepine nucleus in the synthesized compounds, antioxidant property of some synthesized oxazolopyrazoloazepines I was investigated by diphenyl-picrylhydrazine radical trapping and power of ferric reduction experiment Short time of reaction, high yields of product, easy separation of catalyst and products are some advantages of this procedure.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Recommanded Product: Ethyl 3-bromo-2-oxopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Quality Control of 70-23-5.

Savari, Mehdi;Varasteh-Moradi, Ali;Sayyed-Alangi, S. Zahra;Hossaini, Zinatossadat;Zafarmehrabian, Ramin research published 《 Ag/Fe₃O₄/TiO₂@MWCNTs as a reusable organometallic nanocatalyst promoted green synthesis of new pyridobenzoazepines: Study of biological activity and reduction of organic pollutants》, the research content is summarized as follows. In this research, Ag/Fe₃O₄/TiO₂@MWCNTs magnetic nanocomposites synthesized using water extract of Spinacia oleracea leaves, and the high performance of synthesized catalyst was confirmed by employing it in the multicomponent reaction of isatoic anhydride, N-methylimidazole, α-haloketones, electron-deficient acetylenic compounds, ammonium acetate, and Me epoxide in water at ambient temperature for the preparation of new pyridobenzoazepine derivatives such as I [X = H, Me, NO₂, etc.; R¹ = Me, Et; R² = CO₂Et, 4-MeC₆H₄, 4-MeOC₆H₄, etc.] in high yields. Also, the catalytic activity of the green synthesized Ag/Fe₃O₄/TiO₂@MWCNTs was evaluated in the reduction of organic pollutants such as 4-nitrophenol in water at mild conditions. The results indicated that the biosynthesized magnetic nanocomposites (MNCs) have very high and effective catalytic activity for organic pollutants within few seconds. The synthesized compounds have OH group in their structure and for this reason might be showed good antioxidant activity. Also, employing Gram-pos. and Gram-neg. bacteria in the disk diffusion procedure confirmed antimicrobial effect of the some pyridobenzoazepine derivatives The results showed that synthesized compounds prevented the bacterial growth. This used procedure for preparation of pyridobenzoazepine derivatives have some advantages such as low reaction time, product with high yields, and simple separation of catalyst and products.

Quality Control of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 19111-87-6, formula is C18H11Br, Name is 2-Bromotriphenylene, Formula: C18H11Br

Sato, Takeo;Shimada, Shigeru;Hata, Kazuo research published 《 Photo-aryl coupling and related reactions. II. Formation of triphenylenes from halo-o-terphenyls》, the research content is summarized as follows. Electronic effects on the photochem. conversion of o-terphenyl to triphenylene were examined by comparing the uv irradiation reaction, carried out in benzene using iodine as an oxidant, of three classes of o-terphenyl derivatives, 4- (I) and 4′-substituted (II) and 4,4”-disubstituted derivatives (III). While a strong electron-withdrawing group such as nitro group, hindered the cyclization reaction to occur, methoxy, fluoro, chloro and bromo compounds afforded the corresponding triphenylene derivatives With bromo and iodo compounds, however, a complex mixture of the products resulted due to photochem. cleavage of a carbon-halogen bonding, which led to the formation of phenylation products and hence phenyltriphenylenes together with reduction products. Further, with iodo compounds, it was found that no oxidant was necessary to effect the cyclodehydrogenation reaction since iodine was liberated during the photolysis. Possible pathways for the formation of the photolysis products from bromo and iodo compounds were discussed in relation to the relative rates of carbon-halogen cleavage and cyclization reactions. Comparison among three classes of halo compounds indicated that, with the exception of iodides, the cyclization reaction occurred more readily with type II compounds than type I compounds, while type III compounds reacted only with difficulty.

19111-87-6, 2-Bromotriphenylene is a useful research compound. Its molecular formula is C18H11Br and its molecular weight is 307.2 g/mol. The purity is usually 95%.
2-Bromotriphenylene is a brominating agent that has the ability to react with sodium carbonate and emit light. The luminescence of 2-bromotriphenylene can be used as an indicator of the degree of dilution, or how much water is present in a solution. It also emits light when it reacts with chloride ions in a reaction solution. 2-Bromotriphenylene can be used as a polymer matrix to form polymeric films, which are then used as catalysts for organic reactions. The luminescence properties of 2-bromotriphenylene make it suitable for use in functional theory experiments. This chemical compound is relatively low cost, and has been shown to have high yield in catalysis., Formula: C18H11Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene, Formula: C8H9BrO2

Satish, Nagam;Sudhakar, Gangarajula research published 《 Scandium Triflate Catalyzed Nazarov Cyclization of Arylvinyl Epoxides Derived from Alkoxides and Chloro(aryl)carbenes: A Facile Access to Resveratrol-Derived Natural Products》, the research content is summarized as follows. The reaction of arylvinyl alkoxides with chloro(aryl)carbenes provided the corresponding arylvinyl epoxides that underwent Nazarov cyclization in a catalytic amount of scandium triflate, providing easy access to several highly substituted indenes, including some resveratrol-derived natural products.

Formula: C8H9BrO2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organic compounds having carbon bonded to bromine are called organic bromides. Related Products of 90-59-5.

Satheeshkumar, K.;Saravana Kumar, P.;Shanmugapriya, R.;Nandhini, C.;Vennila, K. N.;Elango, Kuppanagounder P. research published 《 An easy to make Hg(II) complex as a selective and sensitive fluorescent turn-on chemosensor for iodide in an aqueous solution based on metal ion displacement mechanism》, the research content is summarized as follows. A simple Schiff base ligand (L) bearing 3,5-dibromo-2-hyrdoxybenzaldehyde fluorophore moiety has rationally been designed, synthesized and characterized. The Hg(II) complex of L was synthesized by simply stirring a mixture of L and HgCl₂ in ethanol at RT and the resultant non-fluorescent complex HgL is found to detect iodide ion selectively, with a turn-on fluorescence in H₂O:DMSO (1:1 volume/volume) medium. The detection of iodide was performed via the metal ion displacement mechanism with a 1:2 (Probe:Iodide) stoichiometry and binding constant of 1.51 × 10⁴ M^-1. Novel HgL complex showed rapid response towards iodide ion with a limit of detection (LOD) as low as 60 nM. Moreover, the sensing mechanism of iodide by the complex is theor. supported by d. functional theory (DFT) and time dependent d. functional theory (TD-DFT) calculations In addition, estimation of iodide in real water samples, table salt and urine sample demonstrate the practical value of the probe.

Related Products of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Organic compounds having carbon bonded to bromine are called organic bromides. Category: bromides-buliding-blocks.

Sartiva, Hazna;Ishida, Momoka;Yoneyama, Kaori;Nishiwaki, Hisashi;Yamauchi, Satoshi research published 《 Plant Growth Suppressive Activity of (R)-3-(7′-Aryl-9′-hydroxyprop-8′-yl)coumarin, Structural Isomer of Z-2-Hydroxybenzylidene-γ-butyrolactone-type Lignan》, the research content is summarized as follows. 3-(7′-Aryl-9′-hydroxyprop-8′-yl)coumarins I [R = H, 4-methoxy, 2-fluoro, etc.], which is a structural isomer of a Z-2-hydroxybenzylidene-γ-butyrolactone-type lignan, was stereoselectively synthesized and subjected to plant growth regulation examination (R)-4′-Methoxyphenyl derivative I [R = 4-methoxy]showed stereospecific plant growth suppressive activity. The significance of the presence of hydroxy group at the 9′-position for the activity was clarified. The effect of the substituent at the 7′-aryl group was also shown. The derivatives I [R = 3-methoxy, 4-methoxy, 4-trifluoromethyl] led to the most significant growth suppression of Italian ryegrass roots. The derivatives 3 I [R = 2-methoxy, 4-methoxy] provided the most growth suppressive activity against lettuce shoots and roots, resp.

Category: bromides-buliding-blocks, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., 402-49-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Product Details of C7H4Br2O2.

Saroya, Sonia;Asija, Sonika;Deswal, Yogesh;Kumar, Naresh;Kumar, Ashwani research published 《 Synthesis, spectral studies, in vitro antimicrobial activity and molecular docking studies of organotin(IV) complexes derived from tridentate Schiff base ligands》, the research content is summarized as follows. In this work, diorganotin complexes of Schiff base ligands, R₂SnL I (R = Bu, Me, Ph; R¹, R² = H, CO₂Me; R³, R⁴ = H, Br, OEt), were synthesized. Schiff base ligands were obtained by the condensation of Me 3-amino-4-hydroxybenzoate and Me 4-amino-3-hydroxybenzoate with salicylaldehyde derivatives in equimolar ratio. The structure of all synthesized compounds were confirmed by several spectroscopic techniques like elemental anal., FT-IR, multinuclear (¹H, ¹³C, and ¹¹⁹Sn) NMR and mass spectrometry. From the spectroscopic data, it was found that the Schiff base ligands are coordinated to tin atom through -ONO donor atoms and tin atom exhibits pentacoordinated geometry in all complexes. The synthesized compounds were assessed for their in vitro antimicrobial potential against four bacterial and two fungal strains. Mol. docking studies of the most potent compound 9 was performed with enzyme 3-oxoacyl-[acyl-carrier-protein] synthase 2 (FabF) of Escherichia coli and sterol 14-alpha demethylase of C. albicans to study their interactions.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., Product Details of C7H4Br2O2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Safety of Methyl 4-bromobutanoate.

Sarode, Bhagyesh R.;Kover, Karen;Friedman, Simon H. research published 《 Visible-Light-Activated High-Density Materials for Controlled in Vivo Insulin Release》, the research content is summarized as follows. In this work, we describe the synthesis, characterization, and ultimate in vivo assessment of second-generation insulin photoactivated depot (PAD) materials. These are the first to use visible light to stimulate insulin release and have an in vivo performance that is 28-fold improved relative to first-generation materials. This improvement is due to two major factors linked to the utilized chem.: (1) we have incorporated the coumarin photocleavable group, which increases the photorelease wavelength into the visible range, enhancing tissue penetration of the light; (2) phototoggling of insulin solubility is produced by linking three insulin mols. to a central bridge via light cleaved groups, and not by bonding to a large polymer. The resulting trimer is, therefore, highly dense (87% insulin dry weight/weight) but retains the insolubility required of the approach. Only after irradiation with visible light is native, soluble insulin is released from the dermal depot. This high d. increases the amount and ease of insulin release, as the d. of photolytic groups is 10-20-fold higher than in polymer-based first-generation materials. We have synthesized new azide-terminated coumarin linkers that we react with the amine groups of insulin. Using mass spectrometry methods, we identify the sites of reaction and purify individual isomers, which we demonstrate have in vitro photolysis rates that are within a factor of 2 of each other. We then reacted these terminal azide groups with a tridentate strained alkyne linker. We show that the resulting insulin trimer is highly insoluble, but can be milled into injectable particles that release insulin only in response to light from a 406 nm light source. Finally, we demonstrate that these materials have a significantly improved in vivo performance, releasing 28-fold more insulin on a per energy basis than first-generation materials.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Safety of Methyl 4-bromobutanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary