Month: October 2022

Kwon, Hyukmin; Kang, Seokwoo; Park, Sunwoo; Park, Sangshin; Oh, Seyoung; Kang, Yuna; Park, Jongwook published the artcile< New blue emitters including phenanthro[9,10-d]oxazole and bulky side group>, Name: 4-Bromobenzylamine, the main research area is phenanthro oxazole blue emitter photoluminescence.

The new blue organic emitter materials, 4′-(3-(phenanthro[9,10-d]oxazol-2-yl -)phenyl)-5′-phenyl-1[1,1′,:2′,1′′-tetraphenyl]-4-carbonitrile (m-PO-PPCN) and 4′-(4-(phenanthro[9,10-d]oxazol-2-yl-)phenyl)-5′-phenyl-1[1,1′,:2′,1′′-tetraphenyl]-4- carbonitrile (p-PO-PPCN) have been successfully synthesized and characterized. In the film state, the UV-visible (UV-Vis) absorption peaks of m-PO-PPCN and p-PO-PPCN were 402 and 413 nm, and the photoluminescence (PL) peaks were 408 and 457 nm. The photoluminescence quantum yield (PLQY) of the two materials was 38.4% and 54.9%. Organic light emitting diodes using m-PO-PPCN and p-PO-PPCN as the emitting layer (EML) showed that m-PO-PPCN had a current efficiency of 0.97 cd/A and an EQE of 1.25%, p-PO-PPCN exhibited current efficiency of 3.69 cd/A and an EQE of 3.46%.

Molecular Crystals and Liquid Crystals published new progress about Absorption. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Name: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sheng, Wenlong; Huang, Fengwei; Dong, Xiaoyun; Lang, Xianjun published the artcile< Solvent-controlled synthesis of Ti-based porphyrinic metal-organic frameworks for the selective photocatalytic oxidation of amines>, COA of Formula: C7H8BrN, the main research area is porphyrinic titanium MOF photocatalyst preparation aralkyl amine photooxidation; Amines; Metal–organic frameworks; Photocatalysis; Selective oxidation; Ti-oxo clusters.

The photocatalytic activity of metal-organic frameworks (MOFs) can be managed by the milieu of synthesis. Herein, N,N′-dimethylacetamide (DMA) and N,N′-diethylformamide (DEF) were employed as solvents for the synthesis of two Ti-based porphyrinic MOFs, namely Ti-PMOF-DMA and Ti-PMOF-DEF, from tetra-Bu orthotitanate and 4,4′,4′′,4′′′-(porphine-5,10,15,20-tetrayl)tetrakis(benzoic acid). Notably, both DMA and DEF were adsorbed onto the Ti-oxo clusters of the two MOFs to shape their properties. Ti-PMOF-DMA was observed with better optoelectronic response and charge transfer than Ti-PMOF-DEF. Moreover, Ti-PMOF-DMA owned a larger pore volume than Ti-PMOF-DEF, imparting more accessible sites to benzyl amines. Ti-PMOF-DMA exhibited better activity in selective photocatalytic aerobic oxidation of benzylamine than Ti-PMOF-DEF. Irradiated by red light-emitting diodes, outstanding results for selective conversion of benzyl amines to imines over Ti-PMOF-DMA were attained. Superoxide radical anion, generated by the electron transfer from porphyrin via Ti-oxo clusters to dioxygen, turned out to be the primary reactive oxygen species. There was generality towards aerobic oxidation of amines to imines and considerable stability for Ti-PMOF-DMA. This work provides a new perspective on the altering MOFs to enhance photocatalytic organic transformations.

Journal of Colloid and Interface Science published new progress about Adsorption. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, COA of Formula: C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Thomas, A. W. published the artcile< Product subclass 1: diaryl ethers>, Electric Literature of 135999-16-5, the main research area is review diaryl ether preparation organic synthesis.

A review of methods to prepare diaryl ethers.

Science of Synthesis published new progress about Aromatic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 135999-16-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2, Electric Literature of 135999-16-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Suresh, Pavithira; Thamotharan, Subbiah; Ganesan, Subramaniapillai Selva published the artcile< Driving NHC organocatalysis on water through hydrophobic hydration for the synthesis of diverse heterocycles and carbocycles>, HPLC of Formula: 3893-18-3, the main research area is heterocycle spirocyclic preparation heterocyclic carbene catalyst water solvent; carbocycle preparation heterocyclic carbene catalyst water solvent.

Unprecedented acceleration in the rate of the N-heterocyclic carbene (NHC) organocatalysis was observed while performing the reaction in water medium with NaCl as an additive during the synthesis of diverse spirooxindole-γ-butyrolactone derivatives, e.g., I. The seminal role of the hydrophobic hydration effect for the acceleration of the reaction was further proven by performing the reaction with antihydrophobic additive LiClO4 and using denser D2O solvent.

Catalysis Communications published new progress about Cycloalkenes Role: SPN (Synthetic Preparation), PREP (Preparation) (cyclopentenes). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, HPLC of Formula: 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Peng, Fu; Zhao, Qian; Huang, Wei; Liu, Shuai-Jiang; Zhong, Ya-Jun; Mao, Qing; Zhang, Nan; He, Gu; Han, Bo published the artcile< Amine-catalyzed and functional group-controlled chemo- and regioselective synthesis of multi-functionalized CF3-benzene via a metal-free process>, Application of C9H7BrO, the main research area is arylpropenal fluoroalkyl cyanobutenoate amine tandem Rauhut Currier reaction; fluoroalkyl biaryl ester preparation chemoselective regioselective green chem; trifluoromethyl oxopentenoate arylpropenal amine tandem Michael reaction; formyl trifluoromethyl terphenyl ester preparation regioselective chemoselective green chem; phenyl butenoate cinnamaldehyde amine chemoselective regioselective Rauhut Currier reaction; diphenyl ester preparation green chem.

A new strategy for the preparation of CF3-containing multi-substituted benzene compounds via an amine-catalyzed reaction under metal-free and air-tolerant conditions was developed. This green reaction provided a functional group-controlled synthetic strategy and the polysubstituted benzene derivatives were obtained in moderate to good yields. Using a tri-substituted alkene containing a cyano group as the starting material, CF3-functionalized benzene compounds with four adjacent substituents were formed via a Rauhut-Currier (RC) reaction-triggered [3 + 3] cascade. When the cyano group was replaced with a benzoyl group, Michael-initialized [4 + 2] aromatization occurred, producing the corresponding CF3-benzene with five contiguous substituent groups. The reaction also features numerous advantages, including excellent chemo- and regioselectivity, extensive substrate scope and environmentally friendly conditions. A simple conversion of an aldehyde into a terminal alkyne was also achieved and the utility of this environmentally compatible method and the one-pot reaction was demonstrated by synthesizing a CF3-functionalized benzene-zidovudine hybrid.

Green Chemistry published new progress about [3+3] Cycloaddition reaction. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application of C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Dake; Berhane, Ilyas A.; Chemler, Sherry R. published the artcile< Copper-Catalyzed Enantioselective Hydroalkoxylation of Alkenols for the Synthesis of Cyclic Ethers>, Name: Methyl 3-bromo-2-(bromomethyl)benzoate, the main research area is THF phthalan isochroman morpholine enantioselective preparation; copper catalyst enantioselective intramol hydroalkoxylation alkenol.

In the presence of Cu(OTf)2 and a nonracemic bis(oxazoline), terminal and 1,1-disubstituted and 1,2-disubstituted alkenols such as I underwent enantioselective intramol. hydroalkoxylation with 1,4-cyclohexadiene as a reducing agent and either MnO2 or Ag2CO3 as oxidant in PhCF3 to yield nonracemic cyclic ethers such as II. Tetrahydrofurans, phthalans, isochromans, and morpholines were prepared from 4- and 5-alkenols using this method; the substrate scope is complementary to existing enantioselective alkene hydroalkoxylations and is broad with respect to substrate backbone and alkene substitution. The method was used for an enantioselective preparation of the antifungal insecticide furametpyr. A polar/radical mechanism involving enantioselective oxycupration followed by homolysis of the copper-carbon bond and hydrogen atom transfer is proposed.

Organic Letters published new progress about Alkenyl alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 337536-14-8 belongs to class bromides-buliding-blocks, and the molecular formula is C9H8Br2O2, Name: Methyl 3-bromo-2-(bromomethyl)benzoate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Espinal-Viguri, Maialen; Neale, Samuel E.; Coles, Nathan T.; Macgregor, Stuart A.; Webster, Ruth L. published the artcile< Room Temperature Iron-Catalyzed Transfer Hydrogenation and Regioselective Deuteration of Carbon-Carbon Double Bonds>, Category: bromides-buliding-blocks, the main research area is iron catalyzed transfer hydrogenation regioselective deuteration alkene; terminal alkyne partial complete hydrogenation; amino alkene alkyne hydrogenation; amine borane transfer hydrogenation.

An iron catalyst has been developed for the transfer hydrogenation of carbon-carbon multiple bonds. Using a well-defined β-diketiminate iron(II) precatalyst, a sacrificial amine and a borane, even simple, unactivated alkenes such as 1-hexene undergo hydrogenation within 1 h at room temperature Tuning the reagent stoichiometry allows for semi- and complete hydrogenation of terminal alkynes. It is also possible to hydrogenate aminoalkenes and aminoalkynes without poisoning the catalyst through competitive amine ligation. Furthermore, by exploiting the sep. protic and hydridic nature of the reagents, it is possible to regioselectively prepare monoisotopically labeled products. DFT calculations define a mechanism for the transfer hydrogenation of propene with nBuNH2 and HBpin that involves the initial formation of an iron(II)-hydride active species, 1,2-insertion of propene, and rate-limiting protonolysis of the resultant alkyl by the amine N-H bond. This mechanism is fully consistent with the selective deuteration studies, although the calculations also highlight alkene hydroboration and amine-borane dehydrocoupling as competitive processes. This was resolved by reassessing the nature of the active transfer hydrogenation agent: exptl., a gel is observed in catalysis, and calculations suggest this can be formulated as an oligomeric species comprising H-bonded amine-borane adducts. Gel formation serves to reduce the effective concentrations of free HBpin and nBuNH2 and so disfavors both hydroboration and dehydrocoupling while allowing alkene migratory insertion (and hence transfer hydrogenation) to dominate.

Journal of the American Chemical Society published new progress about Agostic bond (Fe-H, in theor. mechanistic study). 2725-82-8 belongs to class bromides-buliding-blocks, and the molecular formula is C8H9Br, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xu, Yuliang; Xu, Ze-Jun; Liu, Zhao-Peng; Lou, Hongxiang published the artcile< Visible-light-mediated de-aminative alkylation of N-arylamines with alkyl Katritzky salts>, Product Details of C7H8BrN, the main research area is alkyl tetrahydroisoquinoline preparation; tetrahydroisoquinoline Katritzky salt deaminative alkylation photochem; aryl alkyl aminoester preparation; Katritzky salt aryl aminoester deaminative alkylation photochem.

A visible-light-mediated de-aminative alkylation of N-arylamines was developed, providing direct access to α-amino C-H functionalization of N-arylamines from readily available Katritzky salts under mild conditions to get tetrahydroisoquinolines, e.g., I, and alkyl-N-aryl-aminoesters, e.g., II. In some cases, this operationally simple protocol could be performed in the absence of a photocatalyst. A wide range of substrates and functional groups were tolerated. The utility of this approach was highlighted by its application to the late-state modification of drug mols., natural products and peptides.

Organic Chemistry Frontiers published new progress about Amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Product Details of C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Barroso, Santiago; Joksch, Markus; Puylaert, Pim; Tin, Sergey; Bell, Stephen J.; Donnellan, Luke; Duguid, Stewart; Muir, Colin; Zhao, Peichao; Farina, Vittorio; Tran, Duc N.; de Vries, Johannes G. published the artcile< Improvement in the Palladium-Catalyzed Miyaura Borylation Reaction by Optimization of the Base: Scope and Mechanistic Study>, Category: bromides-buliding-blocks, the main research area is palladium catalyzed Miyaura borylation aryl halide base optimization; Arylboronic acid ester preparation.

Aryl boronic acids and esters are important building blocks in API synthesis. Pd-catalyzed Suzuki Miyaura borylation is the most common method for their preparation This paper describes an improvement of the current reaction conditions. By using lipophilic bases such as K 2-Et hexanoate, borylation reaction could be achieved at 35° in <2 h with very low Pd loading (0.5 mol %). A preliminary mechanistic study shows a hitherto unrecognized inhibitory effect by the carboxylate anion on the catalytic cycle, whereas 2-Et hexanoate minimizes this inhibitory effect. This improved methodol. enables borylation of a wide range of substrates under mild conditions. Journal of Organic Chemistry published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hayashi, Yujiro; Toyoshima, Maya; Gotoh, Hiroaki; Ishikawa, Hayato published the artcile< Diphenylprolinol Silyl Ether Catalysis in an Asymmetric Formal Carbo [3 + 3] Cycloaddition Reaction via a Domino Michael/Knoevenagel Condensation>, Application of C9H7BrO, the main research area is diphenylprolinol silyl ether catalyst unsaturated aldehyde oxopentanedioate stereoselective cycloaddition; Michael reaction Knoevenagel condensation diphenylprolinol silyl ether catalyst; cyclohexenone stereoselective preparation.

Diphenylprolinol silyl ether I (R1 = H, R2 = H, TMS, TBS; R1 = CF3, R2 = TMS) was found to catalyze the formal carbo [3 + 3] cycloaddition reaction through the domino reaction via the Michael reaction, followed by Knoevenagel condensation of the α,β-unsaturated aldehyde and di-Me 3-oxopentanedioate, affording substituted cyclohexenone derivatives, e.g. II, with excellent enantioselectivity.

Organic Letters published new progress about Cycloaddition reaction (asym. formal [3+3]). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application of C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary