Month: October 2022

Dan, Demin; Chen, Fubo; Zhao, Whenshu; Yu, Han; Han, Sheng; Wei, Yongge published the artcile< Chromium-catalysed efficient N-formylation of amines with a recyclable polyoxometalate-supported green catalyst>, Related Products of 3959-07-7, the main research area is formamide preparation; formic acid amine chromium catalyst formylation green chem; polyoxometalate based chromium catalyst preparation crystallinity.

A simple and efficient protocol for the formylation of amines with formic acid, catalyzed by a polyoxometalate-based chromium catalyst was described. Notably, this method showed excellent activity and chemoselectivity for the formylation of primary amines, diamines were successfully employed. Importantly, the chromium catalyst is potentially non-toxic, environmentally benign and safer than the widely used high valence chromium catalysts such as CrO3 and K2Cr2O7. The catalyst can be recycled several times with a negligible impact on activity. Finally, a plausible mechanism was provided based on the observation of intermediate and control experiments

Dalton Transactions published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Related Products of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Liu, Kui; Wang, Gang; Zhang, Zhe-Wen; Shi, Yu-Yang; Ye, Zhi-Shi published the artcile< C-C Bond Activation of Cyclopropanes Enabled by Phosphine-Catalyzed In Situ Formation of High-Strain Methylenecycopropane Intermediate>, Category: bromides-buliding-blocks, the main research area is pentadiene sulfonamide isoindoline preparation; cyclopropane sulfonamide ring opening elaboration phosphine catalyst.

An effective strategy for the ring-opening/elaboration of cyclopropanes by phosphine catalyst is documented, providing the 2,4-pentadiene sulfonamides and isoindolines in moderate to good yields. The key to the success of this reaction is phosphine-catalyzed introduction of a trigonal center into cyclopropanes, which results in the formation of higher ring strain cyclopropylidenemethyl phosphonium salt. Moreover, this methodol. is employed as the key step for the synthesis of bioactive mols.

Organic Letters published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Tu, Yujie; Yu, Yeqing; Zhou, Zhibiao; Xie, Sheng; Yao, Bicheng; Guan, Shujuan; Situ, Bo; Liu, Yong; Kwok, Ryan T. K.; Lam, Jacky W. Y.; Chen, Sijie; Huang, Xuhui; Zeng, Zebing; Tang, Ben Zhong published the artcile< Specific and Quantitative Detection of Albumin in Biological Fluids by Tetrazolate-Functionalized Water-Soluble AIEgens>, Reference of 184239-35-8, the main research area is tetrazolate functionalized fluorescent probe aggregation induced emission albumin; aggregation-induced emission; albumin; diagnostic detection; tetrazolate−lysine interaction; water-soluble fluorescent probe.

The anal. of albumin has clin. significance in diagnostic tests and obvious value to research studies on the albumin-mediated drug delivery and therapeutics. The present immunoassay, instrumental techniques, and colorimetric methods for albumin detection are either expensive, troublesome, or insensitive. Herein, a class of water-soluble tetrazolate-functionalized derivatives with aggregation-induced emission (AIE) characteristics is introduced as novel fluorescent probes for albumin detection. They can be selectively lighted up by site-specific binding with albumin. The resulting albumin fluorescent assay exhibits a low detection limit (0.21 nM), high robustness in aqueous buffer (pH = 6-9), and a broad tunable linear dynamic range (0.02-3000 mg/L) for quantification. The tetrazolate functionality endows the probes with a superior water solubility (>0.01 M) and a high binding affinity to albumin (KD = 0.25μM). To explore the detection mechanism, three unique polar binding sites on albumin are computationally identified, where the multivalent tetrazolate-lysine interactions contribute to the tight binding and restriction of the mol. motion of the AIE probes. The key role of lysine residues is verified by the detection of poly-L-lysine. Moreover, we applied the fluorogenic method to quantify urinary albumin in clin. samples and found it a feasible and practical strategy for albumin anal. in complex biol. fluids.

ACS Applied Materials & Interfaces published new progress about Aggregation-induced emission. 184239-35-8 belongs to class bromides-buliding-blocks, and the molecular formula is C26H18Br2, Reference of 184239-35-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jia, Xiangqing; Nitsch, Joern; Ji, Lei; Wu, Zhu; Friedrich, Alexandra; Kerner, Florian; Moos, Michael; Lambert, Christoph; Marder, Todd B. published the artcile< Triarylborane-Based Helical Donor-Acceptor Compounds: Synthesis, Photophysical, and Electronic Properties>, HPLC of Formula: 576-83-0, the main research area is triarylborane helicene donor acceptor compound fluorescence UV electrochem electronic; boron; charge transfer; fluorescence; helicenes; luminescent.

The synthesis and characterization of 10-(dimesitylboryl)-N,N-di-p-tolylbenzo[c]phenanthren-4-amine (3-B(Mes)2-[4]helix-9-N(p-Tol)2 1) and 13-(dimesitylboryl)-N,N-di-p-tolyldibenzo[c,g]phenanthren-8-amine (3-B(Mes)2-[5]helix-12-N(p-Tol)2 2) are reported herein. Their electrochem. and photophys. properties have been studied exptl. and theor. The donor and acceptor-substituted helicene derivatives exhibit moderate fluorescence quantum yields in THF (Φf=0.48 and 0.61 for 1 and 2, resp.), which are higher than unsubstituted ones (Φf=0.18 for [4]helicene; Φf<0.05 for [n]helicenes (n≥5)). In the solid state, the Φf values are higher (Φf=1.00 and 0.55 for 1 and 2, resp.) than those in solution, most likely due to the restrictions of mol. motions. The S1←S0 transitions of 1 and 2 are predominately HOMO→LUMO transitions. Upon excitation with UV light, the interplanar angle between the two terminal aryl rings of the [5]helix core of 2 decreases (S1 state compared with S0 state), which is similar to placing a spring under an external force. Chemistry - A European Journal published new progress about Band gap. 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, HPLC of Formula: 576-83-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cui, Haishuai; Zhong, Linhao; Lv, Yang; Hao, Fang; Liu, Pingle; Xiong, Wei; Xiong, Shaofeng; Liu, Huajie; Luo, He′an published the artcile< A facile synthesis of in-situ formed amorphous zirconia catalysts for efficient transfer hydrogenation of unsaturated aldehydes>, Computed Properties of 3893-18-3, the main research area is amorphous zirconia catalyst unsaturated aldehyde transfer hydrogenation.

Several metal salts were used for the cinnamaldehyde transfer hydrogenation, and it was found that heterogeneous reactions coexisted in this superficial homogeneous catalytic system. Among these metal salts, Zr(NO3)4·5H2O exhibits the best catalytic performance. Notably, the in-situ formed amorphous zirconia during the reaction is identified as the active site of Zr(NO3)4·5H2O. The in-situ formed zirconia in the presence of cinnamaldehyde (self-selective ZrO2) possesses smaller particle size, better dispersion and more surface hydroxyl groups, which exhibits remarkably enhanced catalytic performance in cinnamaldehyde transfer hydrogenation as compared to the com. nano-zirconia and laboratory-prepared zirconia. The characterization and theor. anal. reveal that the synergistic catalytic effect between zirconium active site and surface hydroxyl groups can effectively activate C=O bonds in cinnamaldehyde and reduce the activation energy barrier, thus significantly improving the transfer hydrogenation performance. Moreover, the self-selective ZrO2 exhibits excellent catalytic performance for a series of unsaturated aldehydes.

Fuel published new progress about Adsorption energy. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Computed Properties of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

D′Addio, Adriano; Malincik, Juraj; Fuhr, Olaf; Fenske, Dieter; Haussinger, Daniel; Mayor, Marcel published the artcile< Gelander Molecules with Orthogonal Joints: Synthesis of Macrocyclic Dimers>, Quality Control of 82-73-5, the main research area is carbazole thiophene macrocycle preparation conformation helicity CD; Geländer molecules; atropisomer; helical chirality; heteroarenes; macrocyclization.

Orthogonal joints, understood as connections with an angle of 90°, were introduced in the design of the “”Gelander”” model compounds 1 and 2. The banister, consisting of a conjugated carbazole dimer linked by either 1,3-butadiyne (2) or a single thiophene (1), wraps around an axis composed of a phthalimide dimer due to the dimensional mismatch of both subunits, which are interconnected by phenylene rungs. The “”Gelander”” structure was assembled from a monomer comprising the 1,4-diaminobenzene rung with one amino substituent as part of a 4-bromo phthalimide subunit forming the orthogonal junction to the axis, and the other as part of a masked 2-ethynyl carbazole as orthogonal joint to the banister. The macrocycle was obtained by two sequential homocoupling steps. A first dimerization by a reductive homocoupling assembled the axis, while an oxidative acetylene coupling served as ring-closing reaction. The formed butadiyne was further derivatized to a thiophene, rendering all carbons of the model compound sp2 hybridized. Both helical structures were fully characterized and chirally resolved. Assignment of the enantiomers was achieved by simulation of chiroptical properties and enantiopure synthesis.

Chemistry – A European Journal published new progress about Chirality. 82-73-5 belongs to class bromides-buliding-blocks, and the molecular formula is C8H3BrO3, Quality Control of 82-73-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhu, Xianjin; Liu, Yong; Liu, Can; Yang, Haijun; Fu, Hua published the artcile< Light and oxygen-enabled sodium trifluoromethanesulfinate-mediated selective oxidation of C-H bonds>, Application of C8H9Br, the main research area is aromatic ketone green preparation; alkyl arene selective oxidation light oxygen sodium trifluoromethanesulfinate mediated; carboxylic acid green preparation; methyl arene selective oxidation light oxygen sodium trifluoromethanesulfinate mediated; aldehyde selective oxidation light oxygen sodium trifluoromethanesulfinate mediated.

Here, for the first time, a novel strategy, light and oxygen-enabled sodium trifluoromethanesulfinate-mediated selective oxidation of C-H bonds, allowing high-value-added aromatic ketones and carboxylic acids to be easily prepared in high-to-excellent yields using readily available alkyl arenes, Me arenes and aldehydes as materials was reported. The mechanistic investigations showed that the treatment of inexpensive and readily available sodium trifluoromethanesulfinate with oxygen under irradiation of light could in situ form a pentacoordinate sulfide intermediate as an efficient photosensitizer. The method represented a highly efficient, economical and environmentally friendly strategy and the light and oxygen-enabled sodium trifluoromethanesulfinate photocatalytic system represents a breakthrough in photochem.

Green Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 2725-82-8 belongs to class bromides-buliding-blocks, and the molecular formula is C8H9Br, Application of C8H9Br.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zheng, Hong-Xing; Shan, Xiang-Huan; Qu, Jian-Ping; Kang, Yan-Biao published the artcile< Strategy for Overcoming Full Reversibility of Intermolecular Radical Addition to Aldehydes: Tandem C-H and C-O Bonds Cleaving Cyclization of (Phenoxymethyl)arenes with Carbonyls to Benzofurans>, Electric Literature of 1013031-65-6, the main research area is haloaralkyl ether aldehyde tandem intermol radical addition cyclization; benzofuran preparation.

An intermol. addition of carbon radicals enabled by a cascade radical coupling strategy is developed. It includes an intermol. alkyl radical addition to a carbonyl group followed by an intramol. alkoxy radical addition to haloarenes and produces substituted benzofurans in high yields. The radical nature of this reaction is explored by radical trapping experiments and EPR anal. The mechanism is investigated by KIE experiments and control experiments This method could provide rapid and practical access to the key intermediate of TAM-16, a safe and potent antibacterial agent for treating tuberculosis, and, therefore, is of great importance for organic synthesis and the pharmaceutical industry.

Organic Letters published new progress about Aldehydes Role: PRP (Properties), RCT (Reactant), RACT (Reactant or Reagent). 1013031-65-6 belongs to class bromides-buliding-blocks, and the molecular formula is C7H6Br2O, Electric Literature of 1013031-65-6.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zeynizadeh, Behzad; Mohammad Aminzadeh, Farkhondeh; Mousavi, Hossein published the artcile< Green and convenient protocols for the efficient reduction of nitriles and nitro compounds to corresponding amines with NaBH4 in water catalyzed by magnetically retrievable CuFe2O4 nanoparticles>, Synthetic Route of 3959-07-7, the main research area is reusable copper ferrite magnetic nanoparticle preparation surface area recyclability; benzonitrile sodium borohydride copper ferrite nanocatalyst reduction green chem; benzylamine preparation; nitrobenzene sodium borohydride copper ferrite nanocatalyst reduction green chem; aniline preparation.

Firstly, CuFe2O4 nanoparticles were prepared by a simple operation. The structure of the mentioned nanoparticles was characterized by Fourier transform IR spectroscopy, X-ray diffraction, SEM, transmission electron microscopy, energy-dispersive X-ray spectroscopy, inductively coupled plasma-optical emission spectrometry, vibrating sample magnetometer and also Brunauer-Emmett-Teller and Barrett-Joyner-Halenda analyses. The prepared magnetically copper ferrite nanocomposite was successfully applied as a simple, cost-effective, practicable and recoverable catalyst on the green, highly efficient, fast, base-free and ligand-free reduction of nitriles and also on the affordable and eco-friendly reduction of nitro compounds with the broad substrate scope to the corresponding amines with NaBH4 in water at reflux in high to excellent yields.

Research on Chemical Intermediates published new progress about Anilines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Synthetic Route of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bonin, Helene; Leuma-Yona, Rodrigue; Marchiori, Bruno; Demonchaux, Patrice; Gras, Emmanuel published the artcile< Highly practical boronic acid surrogates for the Suzuki-Miyaura cross-coupling>, Application In Synthesis of 639520-70-0, the main research area is biaryl preparation; Suzuki Miyaura cross coupling aryl bromide oxazaborocane boronic acid.

Boronic acids and esters are well known substrates for the Suzuki-Miyaura cross-coupling, yet their isolation can sometimes be tedious. We report here that the use of aryl dioxazaborocanes afford a simple isolation procedure while keeping a high efficiency in the cross-coupling process.

Tetrahedron Letters published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 639520-70-0 belongs to class bromides-buliding-blocks, and the molecular formula is C12H16BrNO2, Application In Synthesis of 639520-70-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary