Month: October 2022

In 2017,Gloor, Christian Simon; Denes, Fabrice; Renaud, Philippe published 《Hydrosulfonylation Reaction with Arenesulfonyl Chlorides and Tetrahydrofuran: Conversion of Terminal Alkynes into Cyclopentylmethyl Sulfones》.Angewandte Chemie, International Edition published the findings.Name: Methyl 3-bromopropanoate The information in the text is summarized as follows:

Terminal alkynes such as I underwent reactions with arylsulfonyl chlorides RSO2Cl via radical addition, translocation and cyclization reactions mediated by NaHCO3 either initiated by dilauroyl peroxide or under photochem. conditions (sunlight) in THF to yield cyclopentylmethyl sulfones such as II. When a nonracemic terminal alkyne (99:1 er) underwent the radical addition, translocation and cyclization reaction sequence, the products were formed in 75:25-88:12 er. The results came from multiple reactions, including the reaction of Methyl 3-bromopropanoate(cas: 3395-91-3Name: Methyl 3-bromopropanoate)

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Name: Methyl 3-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Liu, Lixin; Dong, Jianyu; Yan, Yani; Yin, Shuang-Feng; Han, Li-Biao; Zhou, Yongbo. Recommanded Product: 8-Bromooctanoic acid. The article was titled 《Photoredox-catalyzed decarboxylative alkylation/cyclization of alkynylphosphine oxides: a metal- and oxidant-free method for accessing benzo[b]phosphole oxides》. The information in the text is summarized as follows:

By photoredox-catalysis, alkylation/aryl C-H cyclization of readily available alkynylphosphine oxides towards benzo[b]phospholes has been realized under metal- and oxidant-free conditions at room temperature This reaction readily incorporates various functionalized alkyl groups into the benzo[b]phosphole skeletons, representing a mild and versatile tool for the preparation of valuable phosphole compounds The experimental process involved the reaction of 8-Bromooctanoic acid(cas: 17696-11-6Recommanded Product: 8-Bromooctanoic acid)

8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid.Recommanded Product: 8-Bromooctanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Journal of the American Chemical Society included an article by Christiansen, Dylan T.; Tomlinson, Aimee L.; Reynolds, John R.. Category: bromides-buliding-blocks. The article was titled 《New Design Paradigm for Color Control in Anodically Coloring Electrochromic Molecules》. The information in the text is summarized as follows:

A new paradigm is established for the design of conjugated anodically coloring electrochromic mols. It is shown that through cross-conjugation the electronic energy levels of the radical cation state may be controllably tuned independent of the neutral state. It is shown how cross-conjugation can be used to tune the radical cation state independent of the neutral state. Manipulating the oscillator strengths of radical cation transitions allows for tuning of the color by shifting the λmax of the low-energy absorption by over 400 nm. The neutral states of these mols. are UV absorbing, providing solutions that are colorless with L*a*b* values of 100, 0, 0. They are oxidized to vibrantly colored radical cations with absorptions that span the visible spectrum, creating green, yellow, and red chromophores. These mols. are then mixed to create transmissive, colorless blends that switch to opaque black solutions The results came from multiple reactions, including the reaction of 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Category: bromides-buliding-blocks)

1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Category: bromides-buliding-blocks1-Bromo-3,4,5-trimethoxybenzene can be used to synthesize N,N′-diarylated indolo[3,2-b]carbazole derivatives, which can find applications in electrophotography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Combined Extractive Dearomatization, Desulfurization, and Denitrogenation of Oil Fuels Using Deep Eutectic Solvents: A Parametric Study》 was published in Industrial & Engineering Chemistry Research in 2020. These research results belong to Warrag, Samah E. E.; Darwish, Ahmad S.; Abuhatab, Farah O. S.; Adeyemi, Idowu A.; Kroon, Maaike C.; AlNashef, Inas M.. Application In Synthesis of Methyltriphenylphosphonium bromide The article mentions the following:

Industrially, deep dearomatization of oil fuels is achieved via catalytic hydrodearomatization (HDA). However, this process suffers from several drawbacks. The most pronounced disadvantages are the intensive energy consumption and the low efficiency toward some aromatic species. With the aim of lowering energy consumption as well as improving the removal efficiency of this process, selective liquid-liquid extraction was proposed in this work. A phosphonium-based deep eutectic solvent (DES) composed of methyltriphenylphosphonium bromide (MTPPBr) and triethylene glycol (TEG) in a molar ratio equal to 1:4 (MTPPBr/TEG) was selected for this investigation. The DES was characterized by its water content, d., viscosity, and degradation temperature Toluene, thiophene, and quinoline were selected to represent the aromatic species in the oil. However, the oil fuel was represented by n-heptane. Next, the solubility of toluene, thiophene, quinoline, and n-heptane in the pure TEG and MTPPBr/TEG was measured at 298.2 K and 1.01 bar. To assess the selectivities and the solute distribution coefficients of the DES for each compound, liquid-liquid equilibrium (LLE) data for the systems {toluene + n-heptane + MTPPBr/TEG}, {thiophene + n-heptane + MTPPBr/TEG}, and {quinoline + n-heptane + MTPPBr/TEG} were reported at 298.2 K and 1.01 bar. Afterward, a parametric study on an arbitrary oil model of {20% toluene + 2% thiophene + 2% quinoline + 76% n-heptane} was conducted by first testing the single-stage liquid-liquid extraction efficiency for each impurity “”toluene, thiophene, and quinoline”” at 298.2 K and 1.01 bar. Then, the effects of various operating parameters including the extraction temperature, the solvent-to-feed ratio (S/F), and the initial concentration of the impurity were investigated. Moreover, the number of extraction stages was estimated Finally, the effect of the repetitive use of DES as well as the possibility of DES regeneration was studied. The experimental process involved the reaction of Methyltriphenylphosphonium bromide(cas: 1779-49-3Application In Synthesis of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Application In Synthesis of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Defluorinative Functionalization of Pd(II) Fluoroalkyl Complexes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Wade Wolfe, Michael M.; Shanahan, James P.; Kampf, Jeff W.; Szymczak, Nathaniel K.. Synthetic Route of C9H11BrO3 The article mentions the following:

When subjected to arylboranes, anionic trifluoromethyl and difluorobenzyl palladium(II) complexes undergo fluoride abstraction followed by 1,1-migratory insertion. The resulting intermediate fluoroalkyl species can be induced to undergo a subsequent transmetalation and reductive elimination from either an in situ formed fluoroboronate (FB(Ar3)-) or an exogenous boronic acid/ester (ArB(OR)2) and nucleophilic activator, representing a net defluorinative arylation reaction. The latter method enabled a structurally diverse substrate scope to be prepared from either an isolated palladium-CF3 complex, or from Pd(PPh3)4 and other com. available reagents. In the experiment, the researchers used many compounds, for example, 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Synthetic Route of C9H11BrO3)

1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Synthetic Route of C9H11BrO31-Bromo-3,4,5-trimethoxybenzene can be used to synthesize N,N′-diarylated indolo[3,2-b]carbazole derivatives, which can find applications in electrophotography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Piezoelectric Energy Harvesting from a Ferroelectric Hybrid Salt [Ph3MeP]4[Ni(NCS)6] Embedded in a Polymer Matrix》 was written by Vijayakanth, Thangavel; Ram, Farsa; Praveenkumar, Balu; Shanmuganathan, Kadhiravan; Boomishankar, Ramamoorthy. Quality Control of Methyltriphenylphosphonium bromide And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

Organic-inorganic hybrid ferroelecs. are an exciting class of mol. materials with promising applications in the area of energy and electronics. The synthesis, ferroelec. and piezoelec. energy harvesting behavior of a 3d metal ion-containing A4BX6 type organic-inorganic hybrid salt [Ph3MeP]4[Ni(NCS)6] (1) is now presented. P-E hysteresis loop studies on 1 show a remnant ferroelec. polarization value of 18.71 μC cm-2, at room temperature Composite thermoplastic polyurethane (TPU) devices with 5, 10, 15 and 20 wt % compositions of 1 were prepared and employed for piezoelec. energy harvesting studies. A maximum output voltage of 19.29 V and a calculated power d. value of 2.51 mW cm-3 were observed for the 15 wt % 1-TPU device. The capacitor charging experiments on the 15 wt % 1-TPU composite device shows an excellent energy storage performance with the highest stored energies and measured charges of 198.8 μJ and 600 μC, resp. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Quality Control of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Quality Control of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Two color photoflow chemistry for macromolecular design》 was written by Van De Walle, Matthias; De Bruycker, Kevin; Blinco, James P.; Barner-Kowollik, Christopher. Safety of Ethyl 4-bromobutyrate And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

We report a photochem. flow setup that exploits λ-orthogonal reactions using two different colors of light (λ1=350 nm and λ2=410 nm) in sequential online irradiation steps. Critically, both photochem. reactive units (a visible-light reactive chalcone and a UV-activated photo-caged diene) are present in the reaction mixture We demonstrate the power of two color photoflow by the wavelength-selective end group modification of photo-caged polymer end groups and the subsequent polymer ring closure driven by a [2+2] cycloaddition Importantly, we evidence that the high energy gate does not induce the visible light reaction of the chalcone, which attests the true λ-orthogonal nature of the flow reaction system. For the first time, this study opens the realm of photoflow reactions to λ-orthogonal photochem. In the part of experimental materials, we found many familiar compounds, such as Ethyl 4-bromobutyrate(cas: 2969-81-5Safety of Ethyl 4-bromobutyrate)

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Safety of Ethyl 4-bromobutyrate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Density Functional Study of Methane Activation by Frustrated Lewis Pairs with Group 13 Trihalides and Group 15 Pentahalides and a Machine Learning Analysis of Their Barrier Heights》 was written by Migliaro, Ignacio; Cundari, Thomas R.. Application In Synthesis of Indium(III) bromide And the article was included in Journal of Chemical Information and Modeling in 2020. The article conveys some information:

Frustrated Lewis pairs (FLP) are an important advancement in metal-free catalysis. FLPs activate a variety of small mols., notably dihydrogen. Methane activation, however, has not been reported despite it being an abundant chem. feedstock. D. functional theory calculations were utilized to elucidate the reaction mechanism of methane activation by triel trihalide and pnictogen pentahalide-ammonia Lewis pairs. Two reaction mechanisms were modeled for methane activation: proton abstraction and hydride abstraction. In all cases, deprotonation was thermodynamically and kinetically favored vs. hydride abstraction. The use of heavier pnictogens and bigger triels were calculated to be more favorable for the activation of methane. To discern factors affecting the activation energies, different descriptors were correlated-ground state thermodn., orbital energies, transition state strain energies, etc.-but no consistent patterns were identified. Thus, machine learning methods were used to correlate ground state parameters to barrier heights. A neural network was used to correlate ground state descriptors (global electrophilicity index, bond dissociation energies, reaction energies) to activation free energies (R2 = 0.90). The experimental process involved the reaction of Indium(III) bromide(cas: 13465-09-3Application In Synthesis of Indium(III) bromide)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.Application In Synthesis of Indium(III) bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Leaping across the visible range: near-infrared-to-violet photon upconversion employing a silyl-substituted anthracene》 was written by Haruki, Rena; Sasaki, Yoichi; Masutani, Kouta; Yanai, Nobuhiro; Kimizuka, Nobuo. Application In Synthesis of 9,10-Dibromoanthracene And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

Upconverting near-IR (NIR) light (λ > 700 nm) to violet light (λ < 450 nm) based on triplet-triplet annihilation (TTA) is achieved for the first time by developing a silyl-substituted anthracene violet emitter and its sensitization by an osmium complex showing a singlet-to-triplet (S-T) absorption in the NIR range. In the experimental materials used by the author, we found 9,10-Dibromoanthracene(cas: 523-27-3Application In Synthesis of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is synthesized by the bromination of anthracene. The bromination reaction is carried out at room temperature using carbon tetrachloride as a solvent. Using 80-85% anthracene as raw material, adding bromine to react for half an hour, the yield is 83-88%.Application In Synthesis of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xu, Ronghua; Gao, Zhenhua; Yu, Yiteng; Tang, Yehua; Tian, Duanshuai; Chen, Tian; Chen, Yibing; Xu, Guangqing; Shi, Enxue; Tang, Wenjun published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《A facile and practical preparation of P-chiral phosphine oxides》.Application In Synthesis of 1-Bromo-3,4,5-trimethoxybenzene The article contains the following contents:

A practical and cost-effective synthetic method of P-chiral diarylalkyl, aryldialkyl, and triaryl phosphine oxides by using readily available chiral diphenyl-2-pyrrolidinemethanol as the auxiliary is developed. The long-standing racemization issue during solvolysis has been addressed and well controlled by employing a suitable solvent, a low reaction temperature, and an appropriate reaction time. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Application In Synthesis of 1-Bromo-3,4,5-trimethoxybenzene)

1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Application In Synthesis of 1-Bromo-3,4,5-trimethoxybenzene1-Bromo-3,4,5-trimethoxybenzene can be used to synthesize N,N′-diarylated indolo[3,2-b]carbazole derivatives, which can find applications in electrophotography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary