Month: October 2022

In 2016,Wang, Kai-Min; Du, Lin; Ma, Yu-Lu; Zhao, Qi-Hua published 《A dual-functional cadmium(II) coordination polymer as a luminescent sensor for selective sensing of iron(III) ions and detecting the temperature》.Transition Metal Chemistry (Dordrecht, Netherlands) published the findings.Safety of Methyl 3-(bromomethyl)benzoate The information in the text is summarized as follows:

A Cd(II) coordination polymer (1), {[Cd2(Ccbp)2(dca)Cl(H2O)3]·4H2O} Ccbp- = 4-carboxy-1-(3-carboxybenzyl)pyridin-1-ium and dca- = dicyanamide, has been synthesized via a hydrothermal reaction and fully characterized by single-crystal x-ray structural anal., FTIR spectroscopy, powder X-ray diffraction, and TGA. Complex 1 has a 2D network structure with uncoordinated functional groups. Its solid-state luminescence properties were measured at room temperature Complex 1 exhibited a high sensitivity for Fe3+ in DMF solutions of mixed metal ions. In addition, the temperature-dependent luminescence properties of 1 have been investigated and show that the complex acts as a luminescent thermometer at 10-90 K. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Safety of Methyl 3-(bromomethyl)benzoate)

Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Moreover, several studies demonstrate that the average proportion of bromine in drugs is significantly higher than that in natural products. Safety of Methyl 3-(bromomethyl)benzoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Huang, Binbin; Li, Yanan; Yang, Chao; Xia, Wujiong. Quality Control of (Bromomethyl)cyclopropane. The article was titled 《Electrochemical 1,4-reduction of α,β-unsaturated ketones with methanol and ammonium chloride as hydrogen sources》. The information in the text is summarized as follows:

A sustainable, chemoselective 1,4-reduction of α,β-unsaturated ketones by means of an electrochem. method is presented, wherein the extremely inexpensive ammonium chloride (NH4Cl) is applied as the only additive. The reaction proceeds smoothly in the air at ambient temperature Mechanistic studies reveal that both NH4Cl and solvent methanol work as hydrogen donors. In the part of experimental materials, we found many familiar compounds, such as (Bromomethyl)cyclopropane(cas: 7051-34-5Quality Control of (Bromomethyl)cyclopropane)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Quality Control of (Bromomethyl)cyclopropane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《A Simple 3D-Printed Enzyme Reactor Paper Spray Mass Spectrometry Platform for Detecting BuChE Activity in Human Serum》 were Yang, Yanmei; Liu, Huimin; Chen, Zhenzhen; Wu, Tianhong; Jiang, Zhongyao; Tong, Lili; Tang, Bo. And the article was published in Analytical Chemistry (Washington, DC, United States) in 2019. Application In Synthesis of 4-Bromobutanoic acid The author mentioned the following in the article:

To achieve personalized healthcare, a quick, accurate, and high-throughput method to detect disease biomarkers is essential. In the traditional practice, mass spectrometry is one of the most powerful tools and is widely studied. However, the test of human serum usually requires complicated sample pretreatment, tedious operations, and precise condition control, especially for the detection of enzymes as biomarkers. As butyrylcholinesterase (BuChE) has an indicative significance in detecting degenerative disease, liver injury, and organophosphate poisoning, the quick quantification of BuChE is of vital importance to the clinic. In this paper, we report the design and fabrication of a portable 3D-printed enzyme reactor paper spray cartridge (3D ER-PS) with integrated functions: temperature control, enzyme reaction, analyte transfer, and paper spray ionization. Coupled with mass spectrometry, quant. testing of BuChE activity in human serum was realized conveniently and accurately. While it only requires very simple sample preparation, the results from current 3D ER-PS approach are well consistent with those obtained using Ellman’s method. This 3D ER-PS platform not only provides a novel solution for the liquid biopsy of BuChE in clinics but also contributes to the development of quick and targeted medical approaches for analyzing other types of serum biomarker mols. in the field of disease diagnosis. In the experimental materials used by the author, we found 4-Bromobutanoic acid(cas: 2623-87-2Application In Synthesis of 4-Bromobutanoic acid)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Application In Synthesis of 4-Bromobutanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Monoamine oxidase-A targeting probe for prostate cancer imaging and inhibition of metastasis》 were Kim, Won Young; Won, Miae; Salimi, Abbas; Sharma, Amit; Lim, Jong Hyeon; Kwon, Seung-Hae; Jeon, Joo-Yeong; Lee, Jin Yong; Kim, Jong Seung. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Safety of 1,6-Dibromohexane The author mentioned the following in the article:

Mitochondrial enzyme monoamine oxidase (MAO-A) is known to be overexpressed in prostate cancer (PCa) cells. Herein, we have developed a two-photon probe (PCP-1) for selectively targeting and imaging the MAO-A in PCa. Supported by enzymic docking and in vitro experiments, PCP-1 showed efficiency to visualize MAO-A overexpressing cells and inhibit their growth and metastasis potential. In the experimental materials used by the author, we found 1,6-Dibromohexane(cas: 629-03-8Safety of 1,6-Dibromohexane)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.Safety of 1,6-Dibromohexane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《A Responsive Magnetic Resonance Imaging Contrast Agent for Detection of Excess Copper(II) in the Liver In Vivo》 were Paranawithana, Namini N.; Martins, Andre F.; Clavijo Jordan, Veronica; Zhao, Piyu; Chirayil, Sara; Meloni, Gabriele; Sherry, A. Dean. And the article was published in Journal of the American Chemical Society in 2019. Related Products of 1129-28-8 The author mentioned the following in the article:

The design, synthesis, and properties of a new gadolinium-based copper-responsive magnetic resonance imaging (MRI) contrast agent is presented. The sensor (GdL1) has high selectivity for copper ions and exhibits a 43% increase in r1 relaxivity (20 MHz) upon binding to 1 equiv of Cu2+ in aqueous buffer. Interestingly, in the presence of physiol. levels of human serum albumin (HSA), the r1 relaxivity is amplified further up to 270%. Addnl. spectroscopic and X-ray absorption spectroscopy (XAS) studies show that Cu2+ is coordinated by two carboxylic acid groups and the single amine group on an appended side chain of GdL1 and forms a ternary complex with HSA (GdL1-Cu2+-HSA). T1-weighted in vivo imaging demonstrates that GdL1 can detect basal, endogenous labile copper(II) ions in living mice. This offers a unique opportunity to explore the role of copper ions in the development and progression of neurol. diseases such as Wilson’s disease. The experimental process involved the reaction of Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Related Products of 1129-28-8)

Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. The most pervasive is the naturally produced bromomethane.Related Products of 1129-28-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Conductivity properties of selected aliphatic monocarboxylic acid anions in water at 298.15 K》 was published in International Journal of Electrochemical Science in 2020. These research results belong to Kinart, Zdzislaw; Tomas, Renato. Synthetic Route of C4H7BrO2 The article mentions the following:

The article presents the elec. conductivity values of sodium salts of four selected monocarboxylic acid derivatives in aqueous solution: those with a chlorine substituent in the peripheral position, i.e. ClCH(CH2)nCOOH; those with a bromine substituent in the peripheral position, i.e. BrCH(CH2)nCOOH; as well as unsaturated sodium salts with a double bond in the peripheral position, i.e. CH2 = CH(CH2)nCOOH; and unsaturated sodium salts with a double bond in the second position, i.e. CH3-CH = CH(CH2)nCOOH. All conductivity measurements were performed at 298.15 K in the concentration range of 0.0005 < c / mol · dm-3 < 0.018. The obtained values allowed the limiting molar conductivities (Λ0m) of the studied electrolytes to be determined using the Fuoss-Justice equation. Based on these (Λ0m) values, the molar limiting conductivity values (λ0A-) for individual anions of the tested electrolytes were calculated and analyzed as a function of carbon chain length. The work also examines the effect of substituent type (Cl or Br) and double bond location on the limiting molar conductivity values of the tested monocarboxylic acid anions and compares them with literature values.4-Bromobutanoic acid(cas: 2623-87-2Synthetic Route of C4H7BrO2) was used in this study.

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Synthetic Route of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Elastic and durable multi-cation-crosslinked anion exchange membrane based on poly(styrene-b-(ethylene-co-butylene)-b-styrene)》 was published in Journal of Polymer Science (Hoboken, NJ, United States) in 2020. These research results belong to Li, Ziming; Li, Conghui; Long, Chuan; Sang, Jing; Tian, Lin; Wang, Fanghui; Wang, Zhihua; Zhu, Hong. Recommanded Product: 1,6-Dibromohexane The article mentions the following:

Anion exchange membranes (AEMs), as the core component of the new generation anion exchange membrane fuel cells (AEMFCs), directly determine the performance and the lifetime of this energy conversion device. Here, AEMs with pendant multiple quaternary ammonium anchored onto the poly(styrene-b-(ethylene-co-butylene)-b-styrene) (SEBS) backbone are synthesized. The comb-shaped copolymer SEBS-C16 is synthesized with N,N-dimethyl-1-hexadecylamine and chloromethylated SEBS to improve solubility, then the multi-cation crosslinker is prepared and grafted on the above backbone to fabricate a series of flexible multi-cation crosslinked SEBS-based AEMs (SEBS-C16-xC4, where x% is the ratio of the crosslinker to polystyrene block) with practical properties. The obtained SEBS-C16-20C4 membrane exhibits a microphase separated morphol. with an interdomain spacing of 18.87 nm. Benefited from the ion channels, SEBS-C16-20C4 shows high conductivity of 77.78 mS/cm at 80°C. Addnl., the prepared SEBS-C16-20C4 membrane with ion exchange capacity of 2.35 mmol/g also exhibits enhanced alk. stability (5.87% hydroxide conductivity decrease in 2 M NaOH solution at 80°C after 1,700 h) and improved mech. properties, compared with the non-crosslinked SEBS-C16 sample. Furthermore, AEMFC single cell performance is evaluated with the SEBS-C16-20C4 membrane, and a maximum power d. of 182 mW/cm2 is achieved at 80°C under H2/O2 conditions.1,6-Dibromohexane(cas: 629-03-8Recommanded Product: 1,6-Dibromohexane) was used in this study.

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.Recommanded Product: 1,6-Dibromohexane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Seasonal variation and gas/particle partitioning of atmospheric halogenated polycyclic aromatic hydrocarbons and the effects of meteorological conditions in Ulsan, South Korea》 was written by Vuong, Quang Tran; Thang, Phan Quang; Nguyen, Tuyet Nam Thi; Ohura, Takeshi; Choi, Sung-Deuk. Recommanded Product: 523-27-3 And the article was included in Environmental Pollution (Oxford, United Kingdom) in 2020. The article conveys some information:

Atm. halogenated polycyclic aromatic hydrocarbons (Halo-PAHs) and parent PAHs were monitored in Ulsan, South Korea for one year (Jan.-Dec. 2015) to investigate their seasonal patterns, gas/particle partitioning behavior, and the impact of meteorol. conditions. The mean concentrations of 24 chlorinated PAHs, 11 brominated PAHs, and 13 parent PAHs in the gaseous and particulate phases were 8.64 and 9.64 pg/m3, 11.6 and 1.62 pg/m3, and 2.17 and 2.40 ng/m3, resp. Winter had the highest ClPAH and PAH levels, with significant contributions from poly-chlorine groups and high-mol.-weight compounds However, BrPAHs showed reverse patterns with the highest concentration in summer and the dominant gaseous fraction throughout the year. In contrast, the effects of the temperature inversion layer and atm. transport from the outside of Ulsan were more apparent for ClPAHs and PAHs, particularly in winter and spring. Regarding gas/particle partitioning, Halo-PAHs exhibited different seasonal behaviors from those of parent PAHs. This study implies that Halo-PAHs and parent PAHs might not share the same atm. behavior, possibly due to different characteristics in atm. reactions with other chems. and particle-size distribution. However, there have been limited studies about the formation of Halo-PAHs and their physicochem. properties; hence, further in-depth investigations are of vital importance. In the experiment, the researchers used 9,10-Dibromoanthracene(cas: 523-27-3Recommanded Product: 523-27-3)

9,10-Dibromoanthracene(cas: 523-27-3) is a dibrominated polycyclic aromatic hydrocarbon (PAH). 9,10-Dibromoanthracene is often used as an energy acceptor and activator in reactions that produce chemiluminescence.Recommanded Product: 523-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary