Month: October 2022

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Kamio, Shintaro; Kageyuki, Ikuo; Osaka, Itaru; Yoshida, Hiroto. Formula: C7H4BrF3. The article was titled 《Anthranilamide (aam)-substituted arylboranes in direct carbon-carbon bond-forming reactions》. The information in the text is summarized as follows:

Anthranilamide (aam)-substituted arylboranes, which were reported to serve as masked boranes in the Suzuki-Miyaura coupling to afford biaryls Ar-4-MeC6H4 [Ar = 2-furanyl, 4-HOC6H4, 2-methoxypyridinyl, etc.] and R1-R2 [R1 = cyclohexanone; R2 = 4-MeC6H4, 2-methoxypyridinyl] in aqueous medium under microwave conditions. The excellent stability of 2-pyridyl-B(aam) toward protodeborylation allowed their smooth cross-coupling.1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Formula: C7H4BrF3) was used in this study.

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Organobromine compounds are produced naturally by marine creatures (sponges, corals, sea slugs, tunicates, sea fans) and seaweed, plants, fungi, lichen, algae, bacteria, microbes, and some mammals. Formula: C7H4BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Energetic structure-property relationships in thermochemistry of halogenosubstituted benzoic acids》 were Zherikova, Kseniya V.; Verevkin, Sergey P.. And the article was published in Journal of Thermal Analysis and Calorimetry in 2019. Related Products of 76006-33-2 The author mentioned the following in the article:

Exptl. thermodn. properties of halogenosubstituted benzoic acids have been evaluated with the help of complementary in silico methods. The study encompassed benzoic acids with fluoro, chloro-, bromo-, and iodo-substituents in the 2-, 3-, and 4-position in the benzene ring, as well as a series of methyl-substituted bromobenzoic acids and dibromobenzoic acids. The high-level quantum-chem. composite method G4 was addnl. used for mutual validation of the theor. and exptl. gaseous standard molar enthalpies of formation. A simple group contribution procedure has been developed for a quick appraisal of the gas-phase and liquid-phase enthalpies of formation as well as of vaporization enthalpies of halogenosubstituted benzoic acids and their poly-Me or poly-halogen-substituted derivatives The system of group-additivity parameters developed in this work can help in the evaluation of new exptl. results or for validation of already available data compiled in comprehensive databases. Moreover, the reliable additive estimates are essential for material sciences or for assessment of chems. fate in environment and in atm.3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Related Products of 76006-33-2) was used in this study.

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals.Related Products of 76006-33-2 The most pervasive is the naturally produced bromomethane.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery》 were Zeng, Xiaodong; Xie, Liru; Chen, Deliang; Li, Shanshan; Nong, Jinxia; Wang, Bo; Tang, Lin; Li, Qianqian; Li, Yang; Deng, Zixin; Hong, Xuechuan; Wu, Mingfu; Xiao, Yuling. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Synthetic Route of C4H7BrO2 The author mentioned the following in the article:

A novel bright near-IR II (NIR-II, 1000-1700 nm) fluorescent probe with excellent water-solubility, superior photostability, and excellent in vitro and in vivo biocompatibility was facilely synthesized for in vivo biomedical imaging of xenograft breast tumor and chem. induced spontaneous breast carcinoma. To the best of our knowledge, it is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated. In the experiment, the researchers used Methyl 3-bromopropanoate(cas: 3395-91-3Synthetic Route of C4H7BrO2)

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Synthetic Route of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Correction: A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery [Erratum to document cited in CA172:249831]》 were Zeng, Xiaodong; Xue, Liru; Chen, Deliang; Li, Shanshan; Nong, Jinxia; Wang, Bo; Tang, Lin; Li, Qianqian; Li, Yang; Deng, Zixin; Hong, Xuechuan; Wu, Mingfu; Xiao, Yuling. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Application In Synthesis of Methyl 3-bromopropanoate The author mentioned the following in the article:

In the published article Liru Xue’s name was not correctly shown; the correction is provided here.Methyl 3-bromopropanoate(cas: 3395-91-3Application In Synthesis of Methyl 3-bromopropanoate) was used in this study.

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Application In Synthesis of Methyl 3-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Selective Hydrogenation of Fatty Nitriles to Primary Fatty Amines: Catalyst Evaluation and Optimization Starting from Octanenitrile》 was written by Hinzmann, Alessa; Groeger, Harald. Application In Synthesis of Bromopentacarbonylmanganese(I) And the article was included in European Journal of Lipid Science and Technology in 2020. The article conveys some information:

In this contribution, an evaluation of the potential of various homogeneous and heterogeneous catalysts for a selective hydrogenation of fatty nitriles toward primary amines is reported exemplified for the conversion of octanenitrile into octane-1-amine as a model reaction. This work describes an optimized hydrogenation process for transforming fatty nitriles to their corresponding primary amines. In general, fatty amines belong to the most applied fatty acid-derived compounds in the chem. industry since such compounds are either directly used in home products such as fabric softeners, dishwashing liquids, car wash detergents, or carpet cleaners or in a broad range of industrial products, for example, lubricating additives, flotation agents, dispersants, emulsifiers, corrosion inhibitors, fungicides, and bactericides, showing addnl. major applications. However, a major concern of current processes is the lack of selectivity and the formation of secondary and tertiary amines as side-products. By modifying a recently developed catalytic system based on manganese as economically attractive and environmentally benign metal component an efficient and selective access to fatty amines when starting from the corresponding nitriles is achieved. For example, hydrogenation of octanenitrile leads to a synthesis of octane-1-amine with >99% conversion and excellent selectivity with formation of secondary and tertiary amine side-products being suppressed to an amount of <1%. In the part of experimental materials, we found many familiar compounds, such as Bromopentacarbonylmanganese(I)(cas: 14516-54-2Application In Synthesis of Bromopentacarbonylmanganese(I))

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Application In Synthesis of Bromopentacarbonylmanganese(I)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Single Wavelength Laser Excitation Ratiometric NIR-II Fluorescent Probe for Molecule Imaging in Vivo》 was written by Ge, Xiaoguang; Lou, Yuheng; Su, Lichao; Chen, Bin; Guo, Zhiyong; Gao, Shi; Zhang, Wenmin; Chen, Tao; Song, Jibin; Yang, Huanghao. Computed Properties of C4H2Br2S And the article was included in Analytical Chemistry (Washington, DC, United States) in 2020. The article conveys some information:

Fluorescence (FL) imaging in the second near-IR window (NIR-II, 1000-1700 nm) has emerged as a promising bioimaging modality that enables noninvasive visualization of deep tissue with an unprecedented resolution However, there is a paucity of studies on high-quality responsive NIR-II FL mols. Herein we report a novel activated NIR-II FL mol., 4,7-bis(5-(4-(diphenylamine)phenyl)-2-thiophene) [1,2,5]selenadiazolo[3,4-f]benzo[c][1,2,5]thiadiazole (SeTT), which exhibits fast and specific responsive capability to hypochlorous acid (HClO). To obtain the NIR-II ratiometric nanoprobe, SeTT was encapsulated on the surface of Er3+-doped down-conversion nanoparticles (DCNP), achieving the DCNP@SeTT nanoprobe. With a single 980 nm laser excitation, the ratiometric FL signal of SeTT at 1150 nm and DCNP at 1550 nm (I1150 nm/I1550 nm) was linearly correlated with the concentration of HClO with a detection limit of 0.4μM. The ratiometric nanoprobe was successfully investigated for variations in HClO concentration in the tumor progression, visualization of anatomical structures of the peritoneal cavity in the mice model with inflammation, and quant. detection of the HClO concentration in a rabbit model of osteoarthritis, achieving a fast response and high selectivity for the detection of HClO. The NIR-II-responsive nanoprobe can serve as a promising and effective tool for highly sensitive monitoring and imaging of HClO in living systems. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromothiophene(cas: 3141-27-3Computed Properties of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.Computed Properties of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Mansour, Ahmed M.; Radacki, Krzysztof; Khaled, Rabaa M.; Soliman, Marwa H.; Abdel-Ghani, Nour T. published an article in 2021. The article was titled 《Phototriggered cytotoxic properties of tricarbonyl manganese(I) complexes bearing α-diimine ligands towards HepG2》, and you may find the article in JBIC, Journal of Biological Inorganic Chemistry.Quality Control of Bromopentacarbonylmanganese(I) The information in the text is summarized as follows:

Reaction between bromo tricarbonyl manganese(I) and N,N’-bis(phenyl)-1,4-diaza-1,3-butadiene ligands, bearing different electron-donating and electron-withdrawing groups R = OCH3, Cl, and NO2 in the ortho- and para-positions on the Ph substituent, afforded [MnBr(CO)3(N-N)]. The influence of the character and position of the substituent on the dark stability and carbon monoxide releasing kinetics was systematically investigated and correlated with the data of the time-dependent d. functional theory calculations The combined UV/visible and IR data clearly revealed that the aerated solutions of [MnBr(CO)3(N-N)] in either coordinating or noncoordinating solvents are dark stable and the fluctuations observed during the incubation period especially in the case of the nitro derivatives may be attributed to the exchange of the axial bromo ligand with the coordinating solvent mols. The free ligands and nitro complexes were noncytotoxic to HepG2 cells under both the dark and illumination conditions. In the dark, Mn(I) compounds, incorporating o-OCH3 and o-Cl, exhibited excellent cytotoxicity with IC50 values of 18.1 and 11.8μM, while their para-substituted analogs were inactive in the dark and active upon the irradiation at 365 nm with IC50 values of 5.7 and 6.7μM, resp.Bromopentacarbonylmanganese(I)(cas: 14516-54-2Quality Control of Bromopentacarbonylmanganese(I)) was used in this study.

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Quality Control of Bromopentacarbonylmanganese(I)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jeong, Myeonggyo; Kang, Seongeun; Torikai, Kohei; Lee, Songyi; Yun, Hwayoung published an article in 2021. The article was titled 《A New Julia-Kocienski Reagent for Convenient Access to the 2-Naphthylmethyl Vinyl Ethers》, and you may find the article in Organic Preparations and Procedures International.Safety of o-Bromobenzaldehyde The information in the text is summarized as follows:

A facile method for the preparation of α-naphthylmethyloxy benzothiazol-2-yl-sulfone I as a new Julia-Kocienski reagent has been developed. This modified reagent converted to be useful to prepare several 2-naphthylmethyl vinyl ethers II (R = H, 4-OMe, 4-F, 2-Br) . In the part of experimental materials, we found many familiar compounds, such as o-Bromobenzaldehyde(cas: 6630-33-7Safety of o-Bromobenzaldehyde)

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Safety of o-BromobenzaldehydeIt is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Computed Properties of C6H5Br2NIn 2020 ,《Made-to-order porous electrodes for supercapacitors: MOFs embedded with redox-active centers as a case study》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Mallick, Arijit; Liang, Hanfeng; Shekhah, Osama; Jia, Jiangtao; Mouchaham, Georges; Shkurenko, Aleksander; Belmabkhout, Youssef; Alshareef, Husam N.; Eddaoudi, Mohamed. The article conveys some information:

In this work, a pre-designed Zr-based-MOF encompassing an organic linker with a redox active core is synthesized and its structure-property relationship as a supercapacitor electrode is investigated. An enhanced performance is revealed by the combination of this MOF’s high porosity and redox core incorporation, which alters its double-layer and pseudocapacitance, resp. An increase in the capacitance performance by a factor of two is achieved via post-synthetic structure rigidification using organic pillars. The experimental part of the paper was very detailed, including the reaction process of 3,5-Dibromoaniline(cas: 626-40-4Computed Properties of C6H5Br2N)

3,5-Dibromoaniline(cas: 626-40-4) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Computed Properties of C6H5Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Reference of Ethyltriphenylphosphonium bromideIn 2021 ,《Electrochemical oxidative Z-selective C(sp2)-H chlorination of acrylamides》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Harnedy, James; Hareram, Mishra Deepak; Tizzard, Graham J.; Coles, Simon J.; Morrill, Louis C.. The article conveys some information:

An electrochem. method for the oxidative Z-selective C(sp2)-H chlorination of acrylamides was developed. This catalyst and organic oxidant free method was applicable across various substituted tertiary acrylamides and provides access to a broad range of synthetically useful Z-β-chloroacrylamides in good yields (22 examples, 73% average yield). The orthogonal derivatization of the products was demonstrated through chemoselective transformations and the electrochem. process was performed on gram scale in flow. After reading the article, we found that the author used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Reference of Ethyltriphenylphosphonium bromide)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.Reference of Ethyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary