Month: October 2022

Product Details of 6630-33-7In 2021 ,《Synthesis of new Schiff bases; Investigation of their in situ catalytic activity for Suzuki C-C coupling reactions and antioxidant activities》 was published in Journal of the Chinese Chemical Society (Weinheim, Germany). The article was written by Yilmaz, Oezguer. The article contains the following contents:

New series of Schiff bases I [R = H, 2-Br, 2,4-di-HOC6H3, etc.] had been synthesized from the reaction between cyclohepta-2,4,6-trien-1-ylmethanamine and different aldehydes, and characterized via using 1H NMR, 13C NMR, FTIR spectroscopy and GC-MS. After the successful synthesis, the in situ catalytic activity of all Schiff bases had been examined for Suzuki C-C cross-coupling reactions using phenylboronic acid, aryl bromides and PdCl2 as a catalyst. Before starting these investigations, reaction conditions were optimized using different bases and solvents. At the end of these reactions, the best efficiency was obtained in Et3N and EtOH. In addition to catalytic investigations, antioxidant activities of all synthesized Schiff bases were examined using DPPH and iron (Fe2+) chelation methods, and IC50 values were calculated While many mols. showed various amounts of antioxidant activity, especially mols. I [R = 2,4-di-HOC6H3, 4-(E)-styryl] showed the best activity compared to butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA), which were used as pos. controls, in DPPH and iron chelating methods, resp. In addition to this study using o-Bromobenzaldehyde, there are many other studies that have used o-Bromobenzaldehyde(cas: 6630-33-7Product Details of 6630-33-7) was used in this study.

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Product Details of 6630-33-7It is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xie, Hui; Hu, Wanshan; Zhang, Fei; Zhao, Changbo; Peng, Tingting; Zhu, Caizhen; Xu, Jian published their research in Journal of Materials Chemistry B: Materials for Biology and Medicine in 2021. The article was titled 《AIE-active polyelectrolyte based photosensitizers: the effects of structure on antibiotic-resistant bacterial sensing and killing and pollutant decomposition》.Related Products of 629-03-8 The article contains the following contents:

A facile and effective multifunctional platform with high bacterial detection sensitivity, good antibacterial activity, and excellent dye decomposition efficiency holds great promise for wastewater treatment. To explore the design rationality and mechanism of material platforms with various integrated components into a single mol. for wastewater treatment applications, herein, four kinds of polyelectrolyte photosensitizers with aggregation-induced emission (AIE) fluorescent units are synthesized and systematically studied to investigate the structure-property relationship that influences the level of conjugation and the hydrophobicity-hydrophilicity balance. By improving the strength of the conjugation, the new AIE photosensitizers DBPVEs (including DBPVE-4 and DBPVE-6) generate a reactive oxygen species (ROS), and a decomposition efficiency of around 55% is obtained for dyes when they are exposed to DBPVEs under white light irradiation, which is higher than those of DBPEs (including DBPE-4 and DBPE-6). More importantly, owing to the longer and more flexible aliphatic chains of DBPVE-6 that facilitate efficient intercalation into cell membranes, the staining ability of DBPVE-6 for methicillin-resistant S. epidermidis (MRSE) is greatly enhanced as compared to that of DBPVE-4. It should be noted that the antibacterial experiment indicates that DBPVE-6 displays potent toxicity to MRSE with 99.9% killing efficiency under white light irradiation This work provides essential theor. and exptl. guidance on the designing of new photosensitizers for wastewater treatment. The results came from multiple reactions, including the reaction of 1,6-Dibromohexane(cas: 629-03-8Related Products of 629-03-8)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.Related Products of 629-03-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Zujin; Wu, Guifang; Gan, Cui; Cai, Guangmei; Zhang, Jianyong; Ji, Hongbing published their research in Colloids and Surfaces, A: Physicochemical and Engineering Aspects in 2021. The article was titled 《Effective adsorption of arsenate, dyes and eugenol from aqueous solutions by cationic supramolecular gel materials》.Computed Properties of C8H8Br2 The article contains the following contents:

Developing efficient separation technologies for wastewater treatment and recovery of natural products is crucial in practical application. Covalent capture of supramol. gel materials and the further surface modification benefit for the improvement in adsorption performance. In the present paper, two kinds of supramol. gels, N,N’,N”-(3-methylpyridine) benzenetriamide (TMPTA) nanotube and N,N’,N”-(3-pyridyl) benzenetriamide (TPTA) nanofiber, were synthesized successfully by supramol. self-assembly of tripodal pyridines and then were further modified with α,α’-dibromo-p-xylene to obtain imidazolium-based gel materials, TMPTA-G-M and TPTA-G-M. They have stable porous structure and pos. charged surfaces with different morphologies. The synthesized gels are characterized by physico-chem. techniques, and the results show that the modification process does not cause significant changes in the morphol. TMPTA-G-M and TPTA-G-M are applied as adsorbents for the selective separation of anionic Congo Red (CR) and cationic dye Rhodamine B (RhB) from aqueous solutions Maximum adsorption amounts (qmax) on TPTA-G-M are 87.95 mg/g for CR and 85.83 mg/g for RB, and on TMPTA-G-M are 372.03 mg/g for CR and 45.64 mg/g for RB, resp. For the arsenate adsorption, TMPTA-G-M showed significantly better adsorption performance with qmax of 66.5 mg/g in solutions at pH = 9 in 10 min. Addnl., TMPTA-G-M is used for the selective separation of eugenol from eugenol acetate which coexist extensively in Clove oil, and it shows excellent adsorption selectivity for eugenol with qmax of 93.59 mg/g at pH = 11. The mechanism study suggests that the morphol. of the gels affects the distribution of charge and further affects the adsorption performance. And the adsorption may involve electrostatic interactions between adsorbent and adsorbate. The results indicate high adsorption ability and regeneration efficiency for TMPTA-G-M, implying the potential application in wastewater treatment and separation of natural product. In the part of experimental materials, we found many familiar compounds, such as 1,4-Bis(bromomethyl)benzene(cas: 623-24-5Computed Properties of C8H8Br2)

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Computed Properties of C8H8Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

SDS of cas: 76006-33-2In 2012 ,《Synthesis, characterization and in vitro antimicrobial screening of quinoline nucleus containing some novel 1,3,4-oxadiazole derivatives》 appeared in Novel Science International Journal of Pharmaceutical Science. The author of the article were Maity, Supriya; Khan, Suroor A.; Ahmad, Shamim. The article conveys some information:

A novel series of 1,3,4-oxadiazole (3a-j) has been synthesized and characterized by means of TLC, m.p. and spectral data like IR, 1H-NMR & Mass spectroscopy. Synthesized compounds were screened for their antibacterial activity against four different strains like Staphylococcus aureus (NCIM 2079), Bacillus subtilis (NCIM 2708), Pseudomonas aeruginosa (NCIM 2242) and Escherichia coli (NCIM 2685) with standard drug ampicillin while antifungal activity was determined against strains like Candida albicans (NCIM 22491) with standard drug griseofulvin. On the basis of statistical anal., it was observed that compounds had significant co-relation. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2SDS of cas: 76006-33-2)

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. SDS of cas: 76006-33-2 The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Formula: C6H12Br2In 2021 ,《Quaternary tannic acid with improved leachability and biocompatibility for antibacterial medical thermoplastic polyurethane catheters》 was published in Journal of Materials Chemistry B: Materials for Biology and Medicine. The article was written by Wang, Yue; Liu, Shuaizhen; Ding, Kaidi; Zhang, Yaocheng; Ding, Xuejia; Mi, Jianguo. The article contains the following contents:

The surfaces of indwelling catheters offer sites for the adherence of bacteria to form biofilms, leading to various infections. Therefore, the development of antibacterial materials for catheters is imperative. In this study, combining the strong antibacterial effect of a quaternary ammonium salt (QAS) and the high biocompatibility of tannic acid (TA), we prepared a quaternary tannic acid (QTA) by grafting a synthesized quaternary ammonium salt, di-Me dodecyl 6-bromohexyl ammonium bromide, onto TA. To prepare antibacterial catheters, QTA was blended with thermoplastic polyurethane (TPU) via melt extrusion, which is a convenient and easy-to-control process. Characterization of the TPU blends showed that compared with those of the QAS, dissolution rate and biocompatibility of QTA were significantly improved. On the premise that the introduction of QTA had only a slight effect on the original mech. properties of pristine TPU, the prepared TPU/QTA maintained satisfactory antibacterial activities in vitro, under a flow state, as well as in vivo. The results verified that the TPU/QTA blend with a QTA content of 4% is effective, durable, stable, and non-toxic, and exhibits significant potential as a raw material for catheters. In the experiment, the researchers used 1,6-Dibromohexane(cas: 629-03-8Formula: C6H12Br2)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.Formula: C6H12Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Tang, Qi; Zhang, Hai-Lin; Wang, Yi; Liu, Jing; Yang, Shi-Ping; Liu, Jin-Gang published an article in 2021. The article was titled 《Mitochondria-targeted carbon monoxide delivery combined with singlet oxygen production from a single nanoplatform under 808 nm light irradiation for synergistic anticancer therapy》, and you may find the article in Journal of Materials Chemistry B: Materials for Biology and Medicine.Quality Control of Bromopentacarbonylmanganese(I) The information in the text is summarized as follows:

A multifunctional nanoplatform (1), MnCO@TPP@C-TiO2, which consists of a carrier of carbon-doped TiO2 nanoparticles with surface covalent functionalization of manganese carbonyls and a directing group of triphenylphosphine, was prepared for mitochondria-targeted carbon monoxide (CO) delivery combined with photodynamic therapy (PDT). MnCO@TPP@C-TiO2 selectively localized in the mitochondria of HeLa cells where the overexpressed-H2O2 triggered CO release resulting in mitochondrial damage. And singlet oxygen species generated upon 808 nm near IR light irradiation further destroyed the mitochondria and induced cancer cells apoptosis. Cytotoxicity assays revealed that the nanoplatform with mitochondria-targeted CO delivery and PDT exhibited the highest lethality against cancer cells in comparison with all the other control samples tested, and it showed good dark biocompatibility with normal cells that express low H2O2 levels. This work may provide new insights into combining CO-based gas therapy with traditional PDT for efficient cancer treatment.Bromopentacarbonylmanganese(I)(cas: 14516-54-2Quality Control of Bromopentacarbonylmanganese(I)) was used in this study.

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Quality Control of Bromopentacarbonylmanganese(I)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Roy, Rupam; Khan, Aasif; Dutta, Tanoy; Koner, Apurba Lal published an article in 2022. The article was titled 《Red to NIR-emissive anthracene-conjugated PMI dyes with dual functions: singlet-oxygen response and lipid-droplet imaging》, and you may find the article in Journal of Materials Chemistry B: Materials for Biology and Medicine.Quality Control of 9,10-Dibromoanthracene The information in the text is summarized as follows:

The rich chem. of solution-processable red and near-IR organic emitters has emerged as an attractive and progressive research field because of their particular applications in organic optoelectronics and bioimaging. Three PMI-based fluorophores were synthesized via conjoining anthracene and donor moieties (-Ph, -N,N-PhNMe2) with a PMI core via an acetylene linkage at the peri-position, which helped to attain extensive electronic conjugation, which was reflected in red and NIR-emission in solution The key mol. features to be highlighted here are: all three dyes are strongly emissive in solution, as unveiled by the excellent absolute fluorescence QYs; and they possess tuneable emission properties, guided by the donor strength and a profound Stokes shift. The three fluorescent dyes demonstrated appreciable singlet-oxygen (1O2) sensitivity when photoirradiated with methylene blue (MB) in solution, showing a substantial blue-shift in emission in a ratiometric manner. Further, the treatment of dye-MB solution with alpha-tocopherol (1O2 scavenger) validated the presence of 1O2 as the only oxidizing species generated by MB in solution Computational investigations gave insight into the twisting of donor moieties in their ground-state optimized geometries, the modulation of the FMO energy gap, and the thermodn. feasibility of the 1O2 reaction. Finally, via taking advantage of the red and NIR-emission, we successfully utilized one of the fluorophores as a lipid-droplet marker for bioimaging in HepG2 cells. In the experiment, the researchers used 9,10-Dibromoanthracene(cas: 523-27-3Quality Control of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) can be sublimated and oxidized to generate anthraquinone. Soluble in hot benzene and hot toluene, slightly soluble in alcohol, ether and cold benzene, insoluble in water.Quality Control of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Application In Synthesis of Ethyltriphenylphosphonium bromideIn 2022 ,《Regio-regular and cross-conjugated poly(thienylene vinylene)s through acyclic diene metathesis》 appeared in Journal of Polymer Science (Hoboken, NJ, United States). The author of the article were Bader, Yousef M. Katba; Guan, Chao; Qin, Yang. The article conveys some information:

Poly(thienylene vinylene)s (PTV’s) are early examples of conjugated polymers but have not been extensively studied when compared with closely analogous polythiophenes. PTV’s synthesized through previously reported techniques are similar in structures that contain various alkyl or alkoxy side-chains that exert limited impact on the polymer electronic properties. Herein, we report the preparation of a series of regio-regular PTV’s (rr-PTV’s) bearing cross-conjugated side-chains through ADMET polymerization of a common brominated di(thienylene vinylene) (DTV) monomer followed by PPM reactions on the resulting brominated PTV. These new polymers contain a bulky silyloxy alkyl side-chain and a functionalized thiophene moiety on every main-chain thiophene unit, and their regio-regular placement is confirmed by NMR spectroscopy. The thienyl based side-groups broaden polymer absorption ranges and at the same time lead to uncommon emission properties that are results of light-induced charge transfer events between the polymer main-chains and side-chains. Removal of the silyl groups on one of these rr-PTV’s led to insoluble materials and x-ray diffraction experiments on the collected solids displayed distinct scattering peaks that are absent from similarly functionalized regio-random PTV’s reported previously, thus suggesting better crystallinity originated from regio-regularity. In the experiment, the researchers used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Application In Synthesis of Ethyltriphenylphosphonium bromide)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.Application In Synthesis of Ethyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2017,Rodriguez Castanon, Jesus; Sano, Natsuhiro; Shiotsuki, Masashi; Sanda, Fumio published 《Synthesis of poly(1-chloro-2-arylacetylene)s with high cis-content and examination of their absorption/emission properties》.Journal of Polymer Science, Part A: Polymer Chemistry published the findings.Safety of 1-Bromo-2-isopropylbenzene The information in the text is summarized as follows:

A series of 1-chloro-2-arylacetylenes [Cl-CC-Ar, Ar = C6H5 (1), C6H4-p-iPr (2), C6H4-p-OiPr (3), C6H4-p-NHC(O)OtBu (4), and C6H4-o-iPr (5)] were polymerized using (tBu3P)PdMeCl/silver trifluoromethanesulfonate (AgOTf) and MoCl5/SnBu4 catalysts. The corresponding polymers [poly(1)-poly(5)] with weight-average mol. weights of 6500-690,000 were obtained in 10-91% yields. THF-insoluble parts, presumably high-mol. weight polymers, were formed together with THF-soluble polymers by the Pd-catalyzed polymerization The Pd catalyst polymerized nonpolar monomers 1 and 2 to give the polymers in yields lower than the Mo catalyst, while the Pd catalyst polymerized polar monomers 3 and 4 to give the corresponding polymers in higher yields. The 1H NMR and UV-vis absorption spectra of the polymers indicated that the cis-contents of the Pd-based polymers were higher than those of the Mo-based polymers, and the conjugation length of the Pd-based polymers was shorter than that of the Mo-based polymers. Pd-based poly(5) emitted fluorescence most strongly among poly(1)-poly(5). © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym.Chem. 2016. In the experiment, the researchers used 1-Bromo-2-isopropylbenzene(cas: 7073-94-1Safety of 1-Bromo-2-isopropylbenzene)

1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. Safety of 1-Bromo-2-isopropylbenzene The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 1970,Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation) included an article by Sharnin, G. P.; Moisak, I. E.; Gryazin, E. E.. Quality Control of 3,3”,5,5”-Tetrabromo-5′-(3,5-dibromophenyl)-1,1′:3′,1”-terphenyl. The article was titled 《Synthesis of 1,3,5,-triphenylbenzene derivatives with fixed position of the functional groups》. The information in the text is summarized as follows:

PhCOMe and 9 acetophenones containing electron-withdrawing substituents in the meta and para positions are self-condensed, by using a K2S2O7-H2SO4 mixture, to the corresponding 1,3,5-triphenylbenzene derivatives in 21-75% yield after 6-10 hr at 80-180°. However, 3-HO-, 3-NH2-, 2-NO2-, and 2-ClC6H4COMe resinify under these conditions. The experimental process involved the reaction of 3,3”,5,5”-Tetrabromo-5′-(3,5-dibromophenyl)-1,1′:3′,1”-terphenyl(cas: 29102-67-8Quality Control of 3,3”,5,5”-Tetrabromo-5′-(3,5-dibromophenyl)-1,1′:3′,1”-terphenyl)

3,3”,5,5”-Tetrabromo-5′-(3,5-dibromophenyl)-1,1′:3′,1”-terphenyl(cas: 29102-67-8) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. The most pervasive is the naturally produced bromomethane.Quality Control of 3,3”,5,5”-Tetrabromo-5′-(3,5-dibromophenyl)-1,1′:3′,1”-terphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary