Month: October 2022

In 2019,Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy included an article by Liu, Ji-lin; Xu, Chun-ling; Yang, Ting; Hu, Zhi-ru; Zhang, Zhi-quan; Feng, Guo-dong. Reference of Ethyl 4-bromobutyrate. The article was titled 《Developed a novel sensor based on fluorescent graft conjugated polymer for the determination of aristolochic acid in traditional Chinese medicine》. The information in the text is summarized as follows:

A novel fluorescent graft conjugated polymer (poly (2, 5-bis (Polyethylene glycol oxybutyrate)-1, 4-phenylethynylene-alt-1, 4-phenyleneethynylene, PPE-OB-PEG)) has been designed and synthesized for the determination of aristolochic acid (AA). The detection conditions and detection characters of PPE-OB-PEG were systematically explored in this work. The fluorescence intensity of PPE-OB-PEG changes with the different concentration of AA. PPE-OB-PEG has a good linear range towards AA from 1.00×10-7 to 8.00×10-5 mol L-1 and the limit of detection (LOD) is 3.00×10-8 mol L-1 (S/N = 3). PPE-OB-PEG have been applied to detect AA in traditional Chinese medicine samples and the results are satisfactory. The exptl. results show that PPE-OB-PEG can be used as a fluorescence probe for rapid and sensitive detection of AA. In addition to this study using Ethyl 4-bromobutyrate, there are many other studies that have used Ethyl 4-bromobutyrate(cas: 2969-81-5Reference of Ethyl 4-bromobutyrate) was used in this study.

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Reference of Ethyl 4-bromobutyrate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Formula: C6H12Br2In 2022 ,《A cationic BODIPY photosensitizer decorated with quaternary ammonium for high-efficiency photodynamic inhibition of bacterial growth》 appeared in Journal of Materials Chemistry B: Materials for Biology and Medicine. The author of the article were Wang, Hongyu; Li, Chaonan; Wu, Qihang; Wen, Hui; Sun, Tingting; Xie, Zhigang. The article conveys some information:

On account of the constant evolution of antibiotic-resistant bacteria, the effects of existing antibacterial materials are being gradually weakened, and the difficulty in curing infectious diseases is increasing. Therefore, more novel antibacterial materials or methods are eagerly required to combat microbial infections. Recently, the advantages of photodynamic therapy in the antibacterial field have gradually been validated. Herein, a trimethylamine (TMA) salt-modified 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) photosensitizer (BODIPY-TMA) was synthesized for antibacterial applications. Due to the pos. charge of the TMA group, enhanced interactions were observed between the prepared BODIPY-TMA nanoparticles (BODIPY-TMA NPs) and neg.-charged bacterial membranes. The BODIPY-TMA NPs showed much better antibacterial effect toward both S. aureus and E. coli compared with their BODIPY-Br NPs counterpart without a pos. charge. Moreover, the BODIPY-TMA NPs efficiently prevented the formation of biofilms and destroyed pre-established biofilms. Thus, such pos.-charged photosensitizers may pave the way for the exploration of highly effective antibacterial agents.1,6-Dibromohexane(cas: 629-03-8Formula: C6H12Br2) was used in this study.

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.Formula: C6H12Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3395-91-3In 2016 ,《Novel 2,4-thiazolidinedione analogues as cytotoxic agents: synthesis and biological screening》 was published in International Journal of Pharmaceutical Research and Bio-Science. The article was written by Shah, Dhaval G.; Patel, Laxman J.. The article contains the following contents:

Novel thiazolidinedione derivatives I (R1 = H, CH2CO2H, CH2CO2Et, etc.; R2 = benzoyl, 2,3-dichlorobenzoyl, 2,4-dichlorobenzoyl, etc.) were synthesized via reaction of N-benzoyl substituted aryl alkyl halide with N-substituted 2,4-thiazolidinedione derivatives and screened for their in vitro cytotoxic activity by MTT assay. The cell lines used were MCF 7 (Breast cancer cell), HELA (Cervical cancer cell line), HEK (Normal epidermal kidney cell line) HEP (Laryngeal cancer cell line) MDA MB 468 (Breast cancer cell line). Screening results showed moderate to good cytotoxic activity for all the compounds Compound I (R1 = CH2CO2H; R2 = 4-chlorobenzoyl) (IC50 = 3.63 μM, HEP, IC50 = 1.07 μM, HEK) and compound I (R1 = CH2CO2H; R2 = 2,3-dichlorobenzoyl) (IC50 = 1.09 μM, HELA, IC50 = 1.989 μM, M468, IC50 = 2.5 μM, MCF7) were found to be most active compared to standard methotrexate (IC50 = 0.22 μM HEP, IC50 = 0.072 μM HEK, IC50 = 0.102 μM HELA, IC50 = 0.152 μM M468, IC50 = 0.100 μM MCF7). Structure activity relationship of synthesized analogs suggested that the attachment of electron withdrawing groups like chloro at R2 position and acetyl group at R1 gave better cytotoxic activity. Activity by hydrogen and acetyl substitution at R1 position linked with N-substituted 2,4-thiazolidinedione scaffold gave better activity in the order of H > CH2COOH. These findings may impart new direction to medicinal chemists and biochemists for further investigations of 2,4-thiazolidinedione containing cytotoxic agents. In the experiment, the researchers used many compounds, for example, Methyl 3-bromopropanoate(cas: 3395-91-3Recommanded Product: 3395-91-3)

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: 3395-91-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Extractive desulfurization of fuel with methyltriphenyl phosphonium bromide- tetraethylene glycol-based eutectic solvents》 was written by Sudhir, Nisha; Yadav, Pooja; Nautiyal, B. R.; Singh, Rakesh; Rastogi, Harsh; Chauhan, Himani. Product Details of 1779-49-3 And the article was included in Separation Science and Technology (Philadelphia, PA, United States) in 2020. The article conveys some information:

In this investigation, we synthesized deep eutectic solvents (DESs) based on methyltriphenyl phosphonium bromide/tetra ethylene glycol (MTPPBr/TetEG) in different molar ratios ranging 1:2, 1:3, 1:4, and 1:6 and characterized by FTIR. The densities and viscosities were also measured at different temperatures Dibenzothiophene (DBT) was extracted using the synthesized DES. Results concluded that at a single stage extraction, a 45% reduction of DBT sulfur compounds from model oil was found even at low-temperature 20°C. In addition to this study using Methyltriphenylphosphonium bromide, there are many other studies that have used Methyltriphenylphosphonium bromide(cas: 1779-49-3Product Details of 1779-49-3) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Product Details of 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《A pillar[5]arene-based fluorescent sensor for sensitive detection of L-Met through a dual-site collaborative mechanism》 was written by Yang, Qing-Yu; Zhang, You-Ming; Ma, Xiao-Qiang; Dong, Hong-Qiang; Zhang, Yun-Fei; Guan, Wen-Li; Yao, Hong; Wei, Tai-Bao; Lin, Qi. HPLC of Formula: 629-03-8 And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. The article conveys some information:

L-Methionine (L-Met) is one of the essential amino acids in human health, efficiently detect L-Met is a significant issue. Herein, a concept “”dual-site collaborative recognition”” had been successfully introduced into the design and achieved high selective and sensitive recognition of L-Met. In order to realize the “”dual-site collaborative recognition””, the authors rationally designed and synthesized an ester functionalized pillar[5]arene-based fluorescent sensor (SP5). And it shows blue Aggregation-induced emission (AIE) fluorescence. In the SP5, the pillar[5]arene group act as C-H···π interactions site, and ester group serve as multi hydrogen bonding acceptor. The SP5 exhibited high selectivity and sensitivity (2.84 × 10-8 M) towards L-Met based on the collaboration of electron-rich cavernous pillar[5]arene group and ester group through C-H···π and H-bond interactions, resp. This “”dual-site collaborative recognition”” mechanism has been studied by 1H NMR, ESI-MS and theor. calculation including frontier orbital (HOMO and LUMO), electrostatic potential (ESP) and the noncovalent interaction (NCI). These theor. calculations not only support the proposed host-guest recognition mechanism, but also provided visualized information on the “”dual-site collaborative recognition”” mode. Furthermore, the concept “”dual-site collaborative recognition”” is an effective strategy for easily detecting biol. mols. In the experimental materials used by the author, we found 1,6-Dibromohexane(cas: 629-03-8HPLC of Formula: 629-03-8)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.HPLC of Formula: 629-03-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bhattarai, Ajaya; Saha, Bidyut; Jaffari, Zeeshan Haider; Rub, Malik Abdul; Alghamdi, Yousef G.; Kumar, Dileep published an article in 2021. The article was titled 《Analysis of interaction between glutamic acid and ninhydrin in the presence of acetate buffer solvent: Impact of gemini (twin-headed) surfactants》, and you may find the article in Colloids and Surfaces, A: Physicochemical and Engineering Aspects.Synthetic Route of C6H12Br2 The information in the text is summarized as follows:

This study analyses the impact of twin-headed gemini surfactants on the interaction between glutamic acid (Glu) and a ninhydrin (Nin) in an acetate buffer. Analyses were observed using a UV-vis spectrophotometer and values of absorbance were recorded at fixed time intermissions. The impact of parameters such as pH, temperature, [Glu], and [Nin] was examined on reaction in gemini surfactants. Using a conductometric technique, elec. conductivities of pure geminis and their mixed systems were noted. Using these data, thus, cmc values of pure geminis and their mixed system were measured. By varying different parameters, the rate constant (kψ-value) was evaluated on finishing each kinetic run using a computer-based procedure. The study showed that twin-headed gemini surfactants demonstrated an excellent impact on the titled reaction over the aqueous system although 16-4-16 catalyzed the study more among geminis and followed the abilities to catalyze at each concentration as 16-4-16 > 16-5-16 > 16-6-16. Our goal was to assess the impact of varied gemini surfactants on rate constant and thus, a pseudo-phase model for micellar activity was applied. A low pos. value of ΔH# with a large neg. ΔS# was obtained in geminis than for aqueous solutions A probable reaction mechanism is discussed.1,6-Dibromohexane(cas: 629-03-8Synthetic Route of C6H12Br2) was used in this study.

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules; synthesis of water-soluble thermoresponsive polylactides.Synthetic Route of C6H12Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Liu, Shanting; Yang, Yue; Deng, Dian-dian; Deng, Xiao-wen; Chen, Zhao; Wang, Xiao-Yan; Pu, Shouzhi published an article in 2022. The article was titled 《Highly emissive D-A-π-D type aggregation-induced emission (AIE) or aggregation-induced emission enhancement (AIEE)-active benzothiadiazole derivatives with contrasting mechanofluorochromic features》, and you may find the article in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy.Product Details of 523-27-3 The information in the text is summarized as follows:

Mechanochromic luminophors with strong solid-state emission are promising candidates for high-contrast mechanochromic luminescence materials. Meanwhile, mech. responsive luminogenic mols. with tricolor switching are highly desirable but are seldom reported. In this work, three anthracene-based donor-acceptor-π-donor (D-A-π-D) type benzothiadiazole derivatives were designed and synthesized. These luminogens showed remarkable aggregation-induced emission (AIE) or aggregation-induced emission enhancement (AIEE) effect. Furthermore, these luminogens exhibited bright and different solid state fluorescence involving yellow-green, yellow and orange colors, and the fluorescence of their solids could be effectively regulated by mech. grinding. For luminogen I, its solid displayed reversible two-color mechanofluorochromic property. As for luminogens II and III, their solids displayed fluorescent colors change from yellow to yellow-green upon slight grinding, and the yellow-green light-emitting solids were converted into orange fluorescent solids after heavy grinding, demonstrating interesting three-color mechanofluorochromism features.9,10-Dibromoanthracene(cas: 523-27-3Product Details of 523-27-3) was used in this study.

9,10-Dibromoanthracene(cas: 523-27-3) can be sublimated and oxidized to generate anthraquinone. Soluble in hot benzene and hot toluene, slightly soluble in alcohol, ether and cold benzene, insoluble in water.Product Details of 523-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: Ethyl 4-bromobutyrateIn 2022 ,《Mineralization of calcium phosphate on two-dimensional polymer films with controllable density of carboxyl groups》 appeared in Journal of Materials Chemistry B: Materials for Biology and Medicine. The author of the article were Zhang, Xinyu; Wu, Lingli; Feng, Guangyuan; Lei, Shengbin. The article conveys some information:

Two-dimensional polymers functionalized with controllable d. of carboxyl groups were constructed with the Langmuir-Blodgett method. Mineralization of calcium phosphate shows significantly different characteristics on these films, which clearly indicates that the d. of carboxy groups plays a determining role in controlling the nucleation and orientated growth of calcium phosphate. In the experimental materials used by the author, we found Ethyl 4-bromobutyrate(cas: 2969-81-5Recommanded Product: Ethyl 4-bromobutyrate)

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: Ethyl 4-bromobutyrate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3141-27-3In 2022 ,《Thienoviologen anolytes for aqueous organic redox flow batteries with simultaneously enhanced capacity utilization and capacity retention》 was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability. The article was written by Liu, Xu; Zhang, Xuri; Li, Guoping; Zhang, Sikun; Zhang, Bingjie; Ma, Wenqiang; Wang, Zengrong; Zhang, Yueyan; He, Gang. The article contains the following contents:

A series of thienoviologen derivatives ([(NPr)2TV]Cl4 and [(OHPr)2TV]Cl2) with a narrow bandgap, high solubility and two-electron transfer properties as anolytes for high-performance aqueous organic redox flow batteries (AORFBs) is reported. Compared with [(OHPr)2TV]Cl2 and other viologen anolytes, [(NPr)2TV]Cl4 showed a higher diffusion coefficient (D, 3.36 x 10-6 cm2 s-1) and electron transfer constant (k0, 0.31 cm s-1). Paired with (ferrocenylmethyl)-trimethylammonium chloride (FcNCl) as the catholyte, the specific capacity of the [(NPr)2TV]Cl4/FcNCl AORFB reached 4.62 A h L-1, and the capacity utilization was up to 86.1%. Moreover, the system also maintained high stability over 300 cycles and delivered 87.9% capacity retention and 99.96% capacity retention per cycle. The simultaneously enhanced capacity retention and capacity utilization of [(NPr)2TV]Cl4-based AORFBs were attributed to the high D and k0, resulting from the smaller mol. volume (583.38 Å3) and appropriate dihedral angle (∼18.37°) between the pyridines. The experimental process involved the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Recommanded Product: 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Recommanded Product: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Crystal structure of tris[4-(naphthalen-1-yl)phenyl]amine》 was written by Yano, Masafumi; Kashiwagi, Yukiyasu; Inada, Yoshinori; Hayashi, Yuki; Mitsudo, Koichi; Kubono, Koji. Synthetic Route of C18H12Br3NThis research focused ontris naphthalen phenyl amine dimer crystal structure hydrogen bond; crystal structure; electroluminescence; hole transporter; organic electronics; tri­aryl­amine. The article conveys some information:

In the title mol., C48H33N, the central N atom shows no pyramidalization, so that the N atom and the three C atoms bound to the N atom lie almost in the same plane. The three para-phenylene rings bonded to the N atom are in a propeller form. All of the naphthalene ring systems are slightly bent. In the crystal, mols. form an inversion dimer, through two pairs of C-H···π interactions, which further interacts with the adjacent dimer via another two pairs of C-H···π interactions, forming a column structure along the a axis. There are no significant interactions between these column structures. The experimental process involved the reaction of Tris(4-bromophenyl)amine(cas: 4316-58-9Synthetic Route of C18H12Br3N)

In general, Tris(4-bromophenyl)amine(cas: 4316-58-9) is often used in the synthesis of porous luminescent covalent–organic polymers (COPs)Synthetic Route of C18H12Br3N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary